# Biostatistics and Bioinformatics Core  (Shared Resources

> **NIH NIH U54** · TEMPLE UNIV OF THE COMMONWEALTH · 2020 · $129,733

## Abstract

PROJECT SUMMARY
Biostatistics and Bioinformatics Core (Shared Resource)
TUFCCC: Eric A. Ross, PhD (Co-Leader) HC: Konstantinos Krampis, PhD (Co-Leader)
The overall goal of the Biostatistics and Bioinformatics Core (BBC) is to facilitate cancer
disparities research at TUFCCC and HC by providing expert experimental design,
bioinformatics, data management, genomics and data analysis support to TUFCCC/HC Cancer
Partnership scientists. Members of the core have substantial knowledge and experience in
biostatistics, bioinformatics, genomics and epidemiology as applied to cancer research. This
highly interactive group of biostatisticians, bioinformatics, informaticians, geneticists and
epidemiologists will serve all Partnership projects, pilot studies and cores and support future
projects and pilot studies.
The specific aims of the Biostatistics and Biostatistics Core are to: (1) Provide expert
consultation for TUFCCC/HC Cancer Partnership investigators in the rigorous design of
experiments and studies, including research proposal development, sample size determination,
randomization procedures, experimental methods and plans for interim reviews and final
analysis. (2) Perform statistical and bioinformatics analyses for TUFCCC/HC Cancer
Partnership investigators using appropriate statistical and computing methodologies, as well as
assist investigators with the writing of statistical and bioinformatics components of manuscripts
and the interpretation and presentation of results. (3) Provide Informatics tools to enhance
TUFCCC/HC Cancer Partnership research. Build cancer research capacity at HC by providing
HC researchers with information systems that facilitate data entry, storage and retrieval. (4)
Provide cost-effective, high-quality genomic and epigenetic services and expertise for the
TUFCCC/HC Cancer Partnership including NextGen sequencing (e.g., DNA-Seq, RNA-Seq) as
well cytogenetic analysis, chromosome and expression microarray solutions as needed. (5)
Enable TUFCCC/HC investigators who may be non-technical users to easily access and
manage large-scale genomic datasets and run bioinformatics data pipelines, through a user-
friendly, web-browser accessible interface.
By providing quantitative and genomics expertise and resources to investigators, and sharing
technical capabilities, the BBC team will support the entire TUFCCC/HC Cancer Partnership
and facilitate achievement of project aims and exploratory analyses beyond those stated.

## Key facts

- **NIH application ID:** 10015232
- **Project number:** 5U54CA221705-03
- **Recipient organization:** TEMPLE UNIV OF THE COMMONWEALTH
- **Principal Investigator:** Eric Andrew Ross
- **Activity code:** U54 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $129,733
- **Award type:** 5
- **Project period:** 2018-09-19 → 2023-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10015232

## Citation

> US National Institutes of Health, RePORTER application 10015232, Biostatistics and Bioinformatics Core  (Shared Resources (5U54CA221705-03). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10015232. Licensed CC0.

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