# Data Management and Analysis Core

> **NIH NIH P20** · UNIVERSITY OF NEBRASKA LINCOLN · 2020 · $400,314

## Abstract

ABSTRACT 
The research to be performed by Nebraska Center for Integrated Biomolecular Communication (CIBC) 
investigators will result in the creation of large, complex datasets, particularly for those researchers with 
projects in metagenomics, metabolomics, and proteomics. Proper experimental design, data generation, and 
subsequent analyses of these datasets will require analytical and computational expertise, access to scientific 
equipment and relevant technical expertise, and large capacity, high-speed computing facilities. Coordinated 
access to such services is often cost prohibitive and non-intuitive for individual laboratories. Another obstacle 
faced by many biomedical researchers, including those affiliated with the CIBC, is the timely and 
comprehensive sharing of research data and research findings with collaborators, stakeholders, and the 
general public. To address these issues, the CIBC will support a Data Management and Analysis Core 
(DMAC) facility. The DMAC facility's long-term objective is to establish a critical, sustainable resource for 
bioinformatics and analytical support, while its near-term goal is to develop and implement hardware, software, 
and expertise in high-throughput bio/chemical data, from multi-type data management to integrative statistical 
analyses. The DMAC will serve CIBC investigators through four specific aims: 1) Design and implement a 
computational platform for data management - including appropriate documentation, long-term backup, and 
basic data analysis - for laboratory experiments conducted by CIBC investigators; 2) Establish a process for 
initiating collaborations with DMAC personnel to enable complex, interdisciplinary projects which may require 
expertise in experimental design, statistical methods, and interpretation; 3) Serve a critical, sustainable role in 
CIBC research by contributing as research collaborators on proposed center projects as detailed in this 
application, as educators in bioinformatics, as authors on publications relevant to the CIBC, and as co- 
investigators on subsequent proposals for both internal and external funding; and 4) Educate CIBC members 
about the role of large-scale omics data in chemical and biochemical research, the potential and caveats of 
such data, and the established pipelines for omic data preprocessing and analysis and facilitate the use of 
such techniques in CIBC projects. The DMAC facility will provide Center members with the resources and 
expertise to address inter- and transdisciplinary research questions focused on understanding chemical and 
biochemical communication pathways for applications in public health. Through the DMAC, CIBC members will 
receive individualized assistance from and in collaboration with Ph.D.-level biomedical scientists within the 
core. CIBC members will also benefit from educational opportunities, which will help build their knowledge 
base in biomedical omics, computation, and analysis. The DMAC will capitalize...

## Key facts

- **NIH application ID:** 10016362
- **Project number:** 5P20GM113126-05
- **Recipient organization:** UNIVERSITY OF NEBRASKA LINCOLN
- **Principal Investigator:** JENNIFER L. CLARKE
- **Activity code:** P20 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $400,314
- **Award type:** 5
- **Project period:** 2016-08-15 → 2021-09-13

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10016362

## Citation

> US National Institutes of Health, RePORTER application 10016362, Data Management and Analysis Core (5P20GM113126-05). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10016362. Licensed CC0.

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