# HMS/BCH Center for Neuroscience Research

> **NIH NIH P30** · HARVARD MEDICAL SCHOOL · 2020 · $475,012

## Abstract

Abstract
Modern neuroscience relies heavily on tools to visualize the structure, and at times the function, of the nervous
system. This includes tools that examine structure at the level of few nanometers (electron microscopy) to
those that examine whole human brain (MRI). Between these extremes are approaches to examine cellular
sub-compartments and organelles, cellular morphology, small-scale circuit organization, and whole rodent or
drosophila brains. Through the Institutional Center Core Grant to Support Neuroscience Research program,
we established at Harvard Medical School and Boston Children's Hospital a Center Imaging Core that supports
research in our community directed at understanding the structure and function of the nervous system in
healthy animals and in models of human disease. The core has been operational for approximately 6 years,
and has facilitated or directly made possible research projects throughout our community. The core operates
both turnkey systems for daily use, specialized microscopes for chronic, high-content, and high-throughput
imaging, as well as custom pipelines for imaging at the highest resolution in tissue and cells. The core has
been successful, supporting over 35 NINDS projects across 27 laboratories. For the upcoming grant period,
we have expanded the set of microscopes available and have reorganized and simplified the administrative
and technical support structure to increase efficiency. Beyond its research mission, the Center will also
continue to serve as a nexus for collaborative interactions across neuroscience communities and an
educational hub for learning about imaging technologies and approaches. Through the sustained development
of this Center, we hope to continue to provide cost-effective and productive services to NINDS researchers
while further deepening ties between these two vibrant neuroscience communities.

## Key facts

- **NIH application ID:** 10016380
- **Project number:** 5P30NS072030-09
- **Recipient organization:** HARVARD MEDICAL SCHOOL
- **Principal Investigator:** Bernardo L Sabatini
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $475,012
- **Award type:** 5
- **Project period:** 2011-09-30 → 2022-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10016380

## Citation

> US National Institutes of Health, RePORTER application 10016380, HMS/BCH Center for Neuroscience Research (5P30NS072030-09). Retrieved via AI Analytics 2026-06-01 from https://api.ai-analytics.org/grant/nih/10016380. Licensed CC0.

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