# Methods Core

> **NIH NIH P50** · WEILL MEDICAL COLL OF CORNELL UNIV · 2020 · $677,553

## Abstract

RESEARCH METHODS CORE ABSTRACT
Our Center proposes a novel deployment focused model that both streamlines behavioral interventions
for late- and mid-life mood disorders and improves their delivery in the community. In response to the
Center's and the field's needs, the Research Methods Core (RMC) will perform the following functions:
1. The RMC will provide operational support to the Center's new and ongoing, independently funded
intervention studies to ensure the highest quality in design, procedures, and analytic strategies.
2. The RMC will develop novel methods outlined in three initiatives:
Initiative 1. Analytic methods to increase the efficiency and the information yield of T2 community-
based effectiveness studies. This initiative supports the Center's program of behavioral interventions
with multiple outcomes and distinct behavioral targets by developing analytic approaches: 1) To
maximize information on intervention outcomes reflecting meaningful dimensions of health and to
reduce sample size requirements; 2) To estimate the indirect effect of longitudinal, continuous
behavioral mediators of outcomes; 3) To increase the information yield of multiple repeated
assessments by mobile health technology and the ability to make comparisons.
Initiative 2. Approaches to integrating multiple big data sources to identify populations in need of novel
interventions and deployment approaches and to policy support. This initiative responds to the Center's
and the field's need to identify subgroups with mood disorders underserved by the current health care
system. Accordingly, it will develop: 1) Innovative approaches for integration of heterogeneously
distributed biomedical big data; 2) Methods for identifying individuals with multiple mental and physical
conditions; and 3) Approaches to characterizing subgroups with poor outcomes. Combined with
stakeholders' input, this information can chart directions for future community interventions. 
Initiative 3: Novel approaches to integrating mobile technology in community interventions taking into
account the skill sets of patients and therapists, and the resources of community settings. Mobile
technology is embedded in the Center's behavioral interventions to augment information available to
community clinicians and to guide them in targeting their sessions. This initiative responds to the
Center's and the field's need for mobile technology accessible to older and middle-aged mental health
consumers and usable at busy community treatment settings.
3. Evaluate the Center's research productivity and impact on the field.
4. Disseminate methodological advances and other Center generated resources.

## Key facts

- **NIH application ID:** 10016868
- **Project number:** 5P50MH113838-04
- **Recipient organization:** WEILL MEDICAL COLL OF CORNELL UNIV
- **Principal Investigator:** Samprit Banerjee
- **Activity code:** P50 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $677,553
- **Award type:** 5
- **Project period:** 2017-09-22 → 2024-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10016868

## Citation

> US National Institutes of Health, RePORTER application 10016868, Methods Core (5P50MH113838-04). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10016868. Licensed CC0.

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