# Developmental Research Program

> **NIH NIH P50** · MAYO CLINIC ROCHESTER · 2020 · $237,274

## Abstract

Project Summary
The Mayo Clinic Breast Cancer SPORE will maximize the number of innovative and high-quality projects in the
Developmental Research Program (DRP). The goal of the DRP is to support innovative and scientifically
meritorious research projects that can be translated into clinically important applications impacting diagnosis
and management of breast cancer to decrease the burden and mortality from this disease. The DRP will: 1)
encourage and solicit innovative translational laboratory, population, and clinical study proposals; 2) encourage
and support interdisciplinary collaboration in translational research in breast cancer; and 3) generate new
hypotheses that can be tested in larger-scale research projects or clinical trials that can impact breast cancer.
The availability of this support provides a stimulus for creativity in the research community, a vehicle for
encouraging the interaction of basic scientists and translational investigators, and an opportunity for expanding
the research spectrum of the SPORE by pursuing new leads based on discoveries and/or opportunities that
arise. The Developmental Research Program will provide $50,000 direct costs for one year ($25,000 from
SPORE funds and $25,000 from Mayo Clinic Cancer Center) to each of six projects. There will be the
possibility, and expectation, of a second year of support based on demonstration of sufficient progress. A
process has been established by the Mayo Clinic Breast Cancer SPORE involving a call for applications and a
formal peer review utilizing the expertise of the Internal Scientific Advisory Committee and other experienced
investigators. Because of the success of this process, it will be continued in the next funding period. Criteria for
selection of projects for funding are based upon scientific merit, originality, qualifications of the applicant, and
translational potential. It is expected that support of developmental research projects will result in generation of
data that will serve as the basis for additional SPORE-sponsored projects or support through peer-reviewed
external grant support. The three main metrics for productivity of the DRP are advancement of DRP projects to
a full Project in the SPORE, and acquisition of extramural funding, and publications by the project awardees.
There have been 27 DRP awardees with three being made recently on September 1, 2015. Regarding the first
metric, half (four) of the eight SPORE projects in the current grant (two) and renewal (two) have a Co-Leader
who was a DRP awardee. Regarding the second metric, the 24 DRP awardees (before September 1, 2015)
have gone on to obtain five R01s (with additional two R01s scored at 1% and 3% for which we expect funding),
four Komen grants, one State of Minnesota grant, one State of Florida grant, eight Foundation grants, an R21
scored at 11% for which the funding decision is pending, and two Breast SPORE Career Enhancement
Awards, in addition to the four awardees who have advanced ...

## Key facts

- **NIH application ID:** 10017904
- **Project number:** 5P50CA116201-15
- **Recipient organization:** MAYO CLINIC ROCHESTER
- **Principal Investigator:** JAMES Newell INGLE
- **Activity code:** P50 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $237,274
- **Award type:** 5
- **Project period:** 2005-09-22 → 2022-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10017904

## Citation

> US National Institutes of Health, RePORTER application 10017904, Developmental Research Program (5P50CA116201-15). Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/grant/nih/10017904. Licensed CC0.

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