# Balloon Angioplasty Inflation Device

> **NIH NIH R44** · MINNESOTA HEALTHSOLUTIONS CORPORATION · 2020 · $761,269

## Abstract

Project Summary/Abstract
We propose the development of a novel balloon angioplasty inflation device for improving the safety and efficacy
of balloon angioplasty. Atherosclerosis is associated with coronary artery disease, ischemic stroke and
peripheral arterial disease. Percutaneous balloon angioplasty, often in conjunction with stent device deployment,
has been associated with prolonged survival, increased quality of life and extended delay of restenosis. There
exists great enthusiasm for percutaneous interventions to resolve atherosclerotic symptoms. Balloon inflation
devices on the market do not adequately consider the molecular composition of the artery nor do they consider
elasticity differences between arterial beds. The proposed project explores a novel technique to promote
improved inflation performance during balloon angioplasty, resulting in less stress on the artery wall to achieve
resultant luminal area. A production prototype device will be developed and evaluated.

## Key facts

- **NIH application ID:** 10019316
- **Project number:** 5R44AG058515-03
- **Recipient organization:** MINNESOTA HEALTHSOLUTIONS CORPORATION
- **Principal Investigator:** Nick Rydberg
- **Activity code:** R44 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $761,269
- **Award type:** 5
- **Project period:** 2017-09-15 → 2021-11-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10019316

## Citation

> US National Institutes of Health, RePORTER application 10019316, Balloon Angioplasty Inflation Device (5R44AG058515-03). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10019316. Licensed CC0.

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