# Organic Synthesis at the Service of Biology and Medicine

> **NIH NIH R50** · SLOAN-KETTERING INST CAN RESEARCH · 2020 · $232,981

## Abstract

Dr. Ouathek Ouerfelli directs the organic synthesis core facility (OSCF) at Memorial Sloan
Kettering Cancer Center (MSK) since 2004. He is committed to provide chemistry services for
the MSK research community and the development of new tools and therapeutic agents for
cancer detection, prevention, and treatment. The core head possesses more than 25 years of
chemistry collaborations and service of MSK investigators, more than half of whom are NCI
grantees. Along these lines, he contributed to major endeavors by eminent colleagues who are
NCI grantees such as Dr. Charles Sawyers (R01 CA155169) which led to an FDA approved drug,
Dr. Scott Lowe (R01 CA155169) with several projects that are showing promise, as well as Dr.
Craig Thompson (RO1 CA168802) for the development of a new cancer markers among others.
He maintains a state-of-the art facility with expert professional personnel in chemical synthesis.
OSCF has now the capability to support medicinal chemistry efforts to evolve agents in support
of MSK investigators. Under his leadership, the core has greatly facilitated preclinical studies at
the Center.

## Key facts

- **NIH application ID:** 10019490
- **Project number:** 5R50CA243895-02
- **Recipient organization:** SLOAN-KETTERING INST CAN RESEARCH
- **Principal Investigator:** Ouathek Ouerfelli
- **Activity code:** R50 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $232,981
- **Award type:** 5
- **Project period:** 2019-09-17 → 2024-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10019490

## Citation

> US National Institutes of Health, RePORTER application 10019490, Organic Synthesis at the Service of Biology and Medicine (5R50CA243895-02). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10019490. Licensed CC0.

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