# The Development and Implementation of a Culturally-Congruent Educational Film designed for PLWHIV to Address Patients' Trauma Histories, Barriers to Care, and CVD Risk Reduction

> **NIH NIH U01** · UNIVERSITY OF CALIFORNIA LOS ANGELES · 2020 · $21,626

## Abstract

Abstract/Project Summary (Parent Award)
Cardiovascular disease (CVD) has emerged as an increasingly important cause of morbidity
and mortality among people living with HIV (PLWHIV). Now that HIV is considered a
manageable chronic disease, the identification and treatment of comorbid medical conditions
including CVD are increasingly the focus of research and clinical attention. What is missing,
however, is yet another critical component of care for PLWHIV: integrated care for histories of
trauma. Experiences of trauma increase the likelihood of HIV infection as well as CVD risk, yet
health care for PLWHIV is rarely coordinated to address these three intersecting issues of HIV,
CVD, and trauma, particularly among those disproportionately affected by HIV, i.e., ethnic
minority patients. Histories of trauma among PLWHIV are associated with inconsistent
treatment adherence and non-adherence, and trauma history alone is associated with poor CVD
outcomes. Failure to address trauma poses significant barriers to the adoption of CVD risk
strategies among PLWHIV. Health systems that coordinate and integrate care across HIV and
chronic conditions such as CVD may provide the infrastructure needed to address the complex
interplay of these conditions and their therapies. We have designed a novel blended, culturally
congruent, evidence-informed care model, “Healing our Hearts, Minds and Bodies” (HHMB), to
address patients' trauma histories and barriers to care, and to prepare patients to engage in
CVD risk reduction. Recognizing the need to ensure that PLWHIV receive CVD guideline-
concordant care, we have also identified implementation strategies to prepare providers and
clinics for addressing CVD risk among their HIV-positive patients. Therefore, using a hybrid type
II effectiveness/implementation study design, the goal of this study is to increase both patient
and organizational readiness to address trauma and CVD risk among PLWHIV. The Specific
Aims are: (1) to assess and enhance organizational readiness for addressing trauma and CVD
risk among ethnic minority PLWHIV; specifically, a phased approach will drive the use of
implementation strategies designed to educate, monitor, and support providers and staff in
adhering to CVD care guidelines; (2) using mixed methods, to (a) evaluate the use and
effectiveness of implementation strategies over time, and (b) identify barriers and facilitators to
organizational adoption of guidelines, provider adherence to guidelines, feasibility, and
sustainability; and (3) to evaluate the effect of HHMB on cognitive-behavioral, emotional, and
physical outcomes among 260 PLWHIV, specifically patient activation, engagement in care,
knowledge of CVD risk, adherence to clinicians' recommendations, cardiovascular health,
mental health symptoms, and satisfaction with care. We will use the RE-AIM framework to guide
the evaluation and the Replicating Effective Programs (REP) Framework to guide the use of
implementation strategies and ...

## Key facts

- **NIH application ID:** 10019763
- **Project number:** 3U01HL142109-02S1
- **Recipient organization:** UNIVERSITY OF CALIFORNIA LOS ANGELES
- **Principal Investigator:** ARLEEN F. BROWN
- **Activity code:** U01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $21,626
- **Award type:** 3
- **Project period:** 2018-08-15 → 2022-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10019763

## Citation

> US National Institutes of Health, RePORTER application 10019763, The Development and Implementation of a Culturally-Congruent Educational Film designed for PLWHIV to Address Patients' Trauma Histories, Barriers to Care, and CVD Risk Reduction (3U01HL142109-02S1). Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/grant/nih/10019763. Licensed CC0.

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