# Core Grant for Vision Research

> **NIH NIH P30** · WASHINGTON UNIVERSITY · 2020 · $627,125

## Abstract

Project Summary.
The Vision Center Core at Washington University serves a large and diverse group of clinicians and basic
scientists studying the biology and pathology of the visual system. In partnership with the Department of
Ophthalmology & Visual Sciences, the Vision Center Core will achieve three main goals. First, it will provide
NEI-funded researchers (and others directly involved in vision science) with access to state-of-the-art
instrumentation and technical support to enhance their individual research efforts. Second, it will enhance the
environment for vision research at Washington University by fostering collaborations and attracting talented
scientists to the field. Third, the Center Core will support the career development of the next generation of
vision scientists. These goals will be achieved by provision of four Resource Cores, supported by an
Administrative Core. Together they will provide the following services:
 1. An Imaging Core will provide technical support in the preparation of ocular tissue for anatomical
 analysis. The core supports immunocytochemistry and in situ hybridization. Core investigators have
 ready access to confocal and multiphoton microscopes and OCT imaging.
 2. A Visual Function Testing (VFT) Core will provide expertise, instrumentation, and training on
 equipment used to quantify visual performance in mice and other model systems. ERG, VEP and
 optomotry analysis are supported.
 3. A Biostatistics & Bioinformatics Core (BBC) will provide statistical and methodological expertise in
 study design, assuring the validity of statistical analyses and reported results. Support is now provided
 for analysis of large data sets, such as those generated in the course of genomic or RNA sequencing
experiments.
 4. A Molecular Genetics Core will provide customized services for the production of transgenic and
 knockout mice using CRISPR/Cas9 technology. Assistance is also provided with design and production
 of gene targeting constructs, viral vectors, IVF services, and sperm/embryo cryopreservation.
Provision of these support services and resources will greatly enhance the research capabilities of
investigators at Washington University and facilitate collaboration among new and established vision scientists.

## Key facts

- **NIH application ID:** 10019875
- **Project number:** 2P30EY002687-42
- **Recipient organization:** WASHINGTON UNIVERSITY
- **Principal Investigator:** Steven Bassnett
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $627,125
- **Award type:** 2
- **Project period:** 1997-04-01 → 2025-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10019875

## Citation

> US National Institutes of Health, RePORTER application 10019875, Core Grant for Vision Research (2P30EY002687-42). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10019875. Licensed CC0.

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