# Chronic Kidney Disease (CKD) Biomarkers Consortium Data Coordinating Center

> **NIH NIH U01** · UNIVERSITY OF PENNSYLVANIA · 2020 · $645,399

## Abstract

Project Summary
The proposed Scientific and Data Coordinating Center (SDCC) for the Chronic Kidney Disease (CKD)
Biomarkers Consortium (BioCon) will support the scientific development and implementation of a broad array
of research protocols conducted by Participating Centers and pilot grant awardees within the Consortium. The
BioCon SDCC will enhance biomarker science in CKD by providing expertise and leadership in epidemiological
study design, biostatistics, laboratory science, stewardship of biosample resources drawn from geographically
dispersed sources, and the collaborative implementation of protocols conducted by the diverse members of the
BioCon research network. The specific aims proposed by the BioCon SDCC are to: 1) enhance biomarker
research in CKD by providing scientific and laboratory leadership and coordination in the design and
implementation of the four broad research protocols being implemented within the BioCon Network, 2) provide
biostatistical expertise and leadership to optimize research designs, outcome measures and analytical
approaches to investigate biomarker-outcome relationships through analysis of single cohort datasets and
through meta-analyses that harmonize data across cohorts, 3) provide the biostatistical expertise and
leadership to enable integration of data across the `omics' space (e.g., metabolomics, proteomics, genomics)
for deeper understanding of biomarker-outcome relationships, 4) provide comprehensive administrative and
logistical support for BioCon by promoting effective communication through the coordination and support of
teleconferences, meetings, subcommittees, developing and managing documentation, maintaining a website
for centralized resources, and preparing standard and special reports of BioCon activities, 5) coordinate and
track the transfer of data and biospecimens between members of the Consortium and relevant laboratories and
repositories, as well as to establish a comprehensive database of biospecimen attributes and biomarker data
for approved research protocols, 6) promote network-wide quality assurance standards, practices and tools,
and engage in quality control of biospecimen assays throughout the Consortium in close collaboration with the
BioCon Quality Assurance Committee, and 7) continue to support the conduct of BioCon Pilot and Feasibility
Projects and the integration of findings from these pilot studies into ongoing research within the Consortium.

## Key facts

- **NIH application ID:** 10020393
- **Project number:** 5U01DK103225-07
- **Recipient organization:** UNIVERSITY OF PENNSYLVANIA
- **Principal Investigator:** Sarah Jeanne Schrauben
- **Activity code:** U01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $645,399
- **Award type:** 5
- **Project period:** 2014-09-18 → 2024-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10020393

## Citation

> US National Institutes of Health, RePORTER application 10020393, Chronic Kidney Disease (CKD) Biomarkers Consortium Data Coordinating Center (5U01DK103225-07). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10020393. Licensed CC0.

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