# Administration and Regulation of Activities associated with The Vanderbilt Urologic Infection Repository, a Resource for Personalized Clinical Discovery

> **NIH NIH P20** · VANDERBILT UNIVERSITY MEDICAL CENTER · 2020 · $87,615

## Abstract

SUMMARY - ADMINISTRATIVE CORE
We propose the Vanderbilt Urologic Infection Repository (VUIR) as a first-in-kind resource for host-pathogen
discovery, one that systematically connects [1] medical data from a vast number of patients who suffer from
urinary tract infections (UTIs) to [2] a biobank of the actual causative organisms. As an informatic and biologic
network, the VUIR will facilitate novel diagnostic and therapeutic strategies to combat UTIs, while providing a
tool to elucidate their underlying pathogenesis. At the same time—given the extensive scope of the VUIR and
its potential for multidisciplinary innovation—the need arises for a strong administrative foundation to coordinate
the program's daily activities and bring to fruition its scientific vision. To these ends, a critical strength of the
VUIR will be its associated Administrative Core (AdCore), a defined personnel structure for organizational
success. The faculty leadership team of the AdCore holds broad expertise in clinical urology (Dr. Douglass
Clayton), microbial pathogenesis (Dr. Maria Hadjifrangiskou), and clinical pathology/laboratory medicine (Dr.
Jonathan Schmitz), further supported by both a Local Executive Committee and External Advisory Committee.
These groups will likewise include strategic representation from informaticians, infectious disease specialists,
hospital epidemiologists, and microbiome experts, providing ongoing thematic direction to the VUIR from the
diverse fields to which the program will contribute. The AdCore will also incorporate dedicated logistical support
from professionals with extensive background in academic and financial administration, as well as web-site
design and event management. In total, this group will ensure that our logistical operations are both proactive
and responsive, coordinating interactions and disseminating specimens/data within and beyond Vanderbilt. The
AdCore will create synergy between the VUIR and complementary institutional structures for precision medicine
and translational discovery, as well as champion pilot projects that build upon VUIR resources. Our ultimate goal,
however, is to create a network of affiliated collaborators across the United States, clinicians and investigators
who could both benefit from and contribute to the combined wealth of data and specimens. Finally, in addition to
supporting scientific innovations, the AdCore will ensure we develop a concomitant footprint in education and
service. Through a combination of workshops, seminars, and immersive experiences, we will connect nationwide
experts in urogenital infection-biology to diverse trainees, from undergraduate students to postdoctoral/clinical
fellows. In addition to content-area education, these interactions will foster networking and career-development
experiences, including opportunities for individuals from underrepresented groups. And reaching beyond
academia, the AdCore will promote outreach to the larger community, building on existing ...

## Key facts

- **NIH application ID:** 10022301
- **Project number:** 5P20DK123967-02
- **Recipient organization:** VANDERBILT UNIVERSITY MEDICAL CENTER
- **Principal Investigator:** Maria Hadjifrangiskou
- **Activity code:** P20 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $87,615
- **Award type:** 5
- **Project period:** — → 2022-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10022301

## Citation

> US National Institutes of Health, RePORTER application 10022301, Administration and Regulation of Activities associated with The Vanderbilt Urologic Infection Repository, a Resource for Personalized Clinical Discovery (5P20DK123967-02). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10022301. Licensed CC0.

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