# Novel Home-Based and Low-Cost ECG Device for periodic evaluation of the presence of atrial fibrillation

> **NIH NIH R42** · GLOBAL INSTRUMENTATION, LLC · 2020 · $340,152

## Abstract

Abstract
Atrial fibrillation (AF) prevalence is estimated to 1% of the general population in the United
States. A shocking 30% to 60% (according to studies) of patients with AF are unaware of their
diagnosis (silent AF). Most AF patients will suffer from congestive heart failure or/and develop
thromboembolic events leading to a dramatic reduction of patients’ quality of life, and a
significant consumption of health care resources. Therefore, AF prevention represents one of
the most significant challenges of modern clinical cardiology. In the proposed project, we will
evaluate a novel concept of patient monitoring utilizing a home-based device called the “Cardio-
Mat”. We will conduct a Phase 1 to design the prototype of the device and test the device in a
small cohort of 20 AF patients. Then, we propose to conduct a Phase 2 project around a clinical
study in which we will enroll 280 AF patients going through either radiofrequency ablation or
electrical cardioversion and monitor these patients at home using an ECG patch and the
proposed new technology. We will follow these patients during 14 days after their procedure.
The primary goal of the study is to evaluate whether the proposed home device can reliably
detect the presence of AF and in an appropriate timely fashion.

## Key facts

- **NIH application ID:** 10023290
- **Project number:** 5R42NR018316-03
- **Recipient organization:** GLOBAL INSTRUMENTATION, LLC
- **Principal Investigator:** JEAN-PHILIPPE Y COUDERC
- **Activity code:** R42 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $340,152
- **Award type:** 5
- **Project period:** 2018-07-06 → 2022-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10023290

## Citation

> US National Institutes of Health, RePORTER application 10023290, Novel Home-Based and Low-Cost ECG Device for periodic evaluation of the presence of atrial fibrillation (5R42NR018316-03). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10023290. Licensed CC0.

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