# Drug Dependence Clinical Research Program

> **NIH NIH P30** · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · 2020 · $782,853

## Abstract

ABSTRACT – OVERALL COMPONENT
This Core Support Center Grant (P30) application requests continued support for an analytical chemistry
laboratory and administrative shared core infrastructure, and support for a pilot project core. The participating,
currently funded, constituent projects continue research programs with human laboratory and treatment clinic
studies of the clinical pharmacology of abused drugs, pharmacotherapies and other treatment strategies to
treat drug abuse and addictions, and studies of the underlying causes and health consequences of drug
addiction with the goal of improving therapies, reducing harm, and guiding public policy. Disciplines
represented by the participating projects and investigators include psychiatry, psychology, internal medicine,
cardiology, occupational medicine, pulmonary medicine, pediatrics, toxicology, environmental public health,
dentistry, and chemistry. Currently, most of the supported projects involve the problems associated with
tobacco addiction, but some are studies of cannabis and these are increasing with grant proposals submitted
or in preparation. We are prepared to support studies of other abused drugs as well, with validated methods
used in past studies, as well as the capability to develop new methods. Projects supported by the Pilot Project
Core will likely involve other drugs of abuse, facilitated by encouraging scholars in UCSF's Learning for Early
Careers in Addiction & Diversity (LEAD) Program whose studies involve a variety of abused substances, to
apply for pilot project funding. Our aims are: (1) To provide a state-of-the-art, well equipped and staffed,
analytical chemistry laboratory resource for the participating projects of drug abuse researchers at UCSF and
at other institutions. (2) A Pilot Project Core with the overarching goal of building a pipeline of investigators
with the skills and experience to conduct high quality, cutting edge, and/or rapid response research in
substance abuse and prevention. (3) To provide administrative support for manuscript preparation, IRB and
related regulatory documents, grants management, and other research administrative services of value
participating projects. (4) To provide statistical consulting services regarding study design and data analysis
strategies, particularly optimal pharmacokinetic analysis to participating projects. The overall objective is to
provide sophisticated analytical laboratory resources with stability of support together with adequate
administrative support responsive to the needs of individual funded constituent scientific projects as those
projects change and evolve. This facility is a cost-effective shared laboratory resource that enhances and
extends research possibilities of investigators currently funded by NIH or other federal or nonfederal agencies
to further our understanding of human psychoactive drug use, abuse and addiction, its health consequences
and its treatment management.

## Key facts

- **NIH application ID:** 10025048
- **Project number:** 2P30DA012393-21
- **Recipient organization:** UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
- **Principal Investigator:** Peyton Jacob
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $782,853
- **Award type:** 2
- **Project period:** 1999-09-01 → 2025-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10025048

## Citation

> US National Institutes of Health, RePORTER application 10025048, Drug Dependence Clinical Research Program (2P30DA012393-21). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10025048. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*