# FOX CORE Phase II Research Core #1 Synthesis

> **NIH NIH P20** · UNIVERSITY OF DELAWARE · 2020 · $149,898

## Abstract

Project Summary
Synthesis and Discovery Core
This Phase II COBRE will continue on its mission to focus a diverse team of scientists on the discovery of new
molecules that probe the function of biological targets. During Phase I, our COBRE developed an instrumentation
core, unique to the state of Delaware, that enabled molecular discovery, purification and analysis. The growth of
our center and the breadth of services offered through our core facilities have prompted us to reorganize this
instrumentation into two core facilities for Phase II: the Synthesis and Discovery (SD) Core Facility and the
Analytical Chemistry Core Facility. The proposed Synthesis and Discovery (SD) Core Facility consists of
instrumentation and infrastructure for small molecule synthesis, high throughput catalyst discovery, computation
and microscopy capabilities that will continue to be broadly used by researchers across the IDeA network and
beyond. During Phase II, we will expand the scope of the facility to provide chemistry services to non-specialists
across the biomedical research spectrum. The facility will enable biologists, biochemists, engineers, and others
access to custom synthesis of molecules they cannot easily make them themselves. The goals of the SD Core
Facility will include (1) the development of an administrative framework for the facility and the recruitment of staff
to provide core services, and (2) establishment of a Custom Synthesis Laboratory (CSL) that will provide a broad
array of synthetic services including small molecule synthesis, purification, chemical assay development and
high throughput reaction development and parallel synthesis.

## Key facts

- **NIH application ID:** 10026271
- **Project number:** 2P20GM104316-06A1
- **Recipient organization:** UNIVERSITY OF DELAWARE
- **Principal Investigator:** Donald Allen Watson
- **Activity code:** P20 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $149,898
- **Award type:** 2
- **Project period:** 2014-09-01 → 2025-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10026271

## Citation

> US National Institutes of Health, RePORTER application 10026271, FOX CORE Phase II Research Core #1 Synthesis (2P20GM104316-06A1). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10026271. Licensed CC0.

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