# Nevada Exploratory Alzheimer's Disease Research Center (NVEADRC)

> **NIH NIH P20** · CLEVELAND CLINIC FOUNDATION · 2020 · $1,149,763

## Abstract

NVEADRC OVERALL
SUMMARY
Health and healthcare disparities in rural vs. urban areas are recognized for several decades, and this is
particularly true for Alzheimer’s disease (AD) and Alzheimer’s disease related dementia (ADRD). Primary care
physicians (PCPs) are rarely equipped with the skills and tools to diagnose the specific type of dementia their
geriatric patients may be suffering. Because of possible long distances between rural areas and the nearest
metropolitan area possessing expert dementia neurologists, some patients may never be diagnosed with
dementia or may be misdiagnosed with the incorrect form of dementia. Previous Alzheimer Disease Research
Centers (ADRCs) have explored rural risks and disparities for AD, but only as satellite programs rather than a
major focus of their activities. Moreover, the literature on demented patients in rural areas is scarce and usually
include only a small number of individuals with limited sets of biomedical data to be able to compare to datasets
from the National Alzheimer’s Coordinating Center (NACC). Such gaps in healthcare offering and lack of reliable
data on rural subjects is motivating us to create the Nevada Exploratory Alzheimer's Disease Research Center
(NVEADRC). Our new Center is based on previous strong collaborations between the Las Vegas Lou Ruvo
Center for Brain Health (LRBCH) and University of Nevada, Las Vegas (UNLV). In Aim 1, we will build the
necessary infrastructure for the operations of our research enterprise. This includes the creation of novel
methodologies and technologies to collect high-quality standardized clinical data in rural settings. In Aim 2, by
utilizing the experience of our Outreach, Recruitment and Engagement Core we will foster our network of
stakeholders, from government entities, to PCPs, down to rural patients themselves to make them feel that they
own the NVEADRC project. In Aim 3, we will plan the transition from an exploratory stage to a full ADRC by
demonstrating the feasibility of collecting longitudinal data from our rural cohort. By adding rural population
information to the NACC set of data, our NVEADRC will provide novel resources that could be used by the broader
AD/ADRD research community, which will significantly contribute to the overall mission of the ADRC network.

## Key facts

- **NIH application ID:** 10037795
- **Project number:** 1P20AG068053-01
- **Recipient organization:** CLEVELAND CLINIC FOUNDATION
- **Principal Investigator:** MARWAN Noel SABBAGH
- **Activity code:** P20 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $1,149,763
- **Award type:** 1
- **Project period:** 2020-08-01 → 2023-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10037795

## Citation

> US National Institutes of Health, RePORTER application 10037795, Nevada Exploratory Alzheimer's Disease Research Center (NVEADRC) (1P20AG068053-01). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10037795. Licensed CC0.

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