# NVEADRC Administrative Core (AC)

> **NIH NIH P20** · CLEVELAND CLINIC FOUNDATION · 2020 · $373,026

## Abstract

NVEADRC ADMINISTRATIVE CORE (AC)
SUMMARY
Our Nevada Exploratory Alzheimer’s Disease Research Center (NVEADRC) is a novel and ambitious research
endeavor aiming at filling a gap from existing ADRCs, which is to collect and share high-quality biomedical data
and specimens from individuals suffering dementia from rural areas. Like for all novel enterprises, the NVEADRC
needs a fully committed leadership to steer and prioritize its activities from the beginning of the project. For this,
we have selected strong leaders with prior ADRC experience to lead the project. The Administrative Core (AC)
is the driving entity for our NVEADRC. It will oversee the research and educational activities of a strong
multidisciplinary team composed of investigators from the Cleveland Clinic Lou Ruvo Center for Brain Health
(LRBCH) and University of Nevada, Las Vegas (UNLV). Most of the investigators are already part of other
collaborative projects, which will greatly facilitate communication between the different Cores early on since most
actors in the enterprise are already aware of the requirements for a successful large collaborative project. We have
set four strategic aims for the AC. In Aim 1, the AC will set up Cores operations with the goal of running this
project over several decades. For this, the AC will call monthly meetings with all Core leaders to address progress
and challenges. The meeting minutes will be sent to all NVEADRC actors to collect feedback for improvement
and suggestions on novel directions. The AC will assure the successful integration of participating rural sites and
investigators, and promote collaborations within the ADRC network. The AC will coordinate the review and
guidance of the NVEADRC by integrating the feedback from an internal and an external advisory committee. In
Aim 2, the AC will work on professionalizing rural dementia healthcare and scientific research by determining
the specific needs of rural medical professionals in neurodegenerative disorders education to create specific
courses and materials (e.g. brochures and videos) for large broadcasting in NV and beyond. Moreover, by
fostering the career development of female faculty the AC wants to offer a transformative experience to build a
pipeline of future female ADRC collaborators and project leaders. In Aim 3, we will leverage our community
connections to inform patients about clinical trials and to recruit rural subjects in our clinical cohort. In Aim 4, the
AC will develop the necessary assessment procedures for compliance and to monitor performance. This includes
compliance with human subjects, scientific integrity, information security and financial policy requirements from
NIH. In addition, the AC will create the procedures for Core assessments to gauge progress based on pre-
determined annual goals. Very importantly, the AC is in charge of the successful transfer of the data captured
from our rural subjects to the National Alzheimer’s Coordinating Center (NACC). Unde...

## Key facts

- **NIH application ID:** 10037796
- **Project number:** 1P20AG068053-01
- **Recipient organization:** CLEVELAND CLINIC FOUNDATION
- **Principal Investigator:** MARWAN Noel SABBAGH
- **Activity code:** P20 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $373,026
- **Award type:** 1
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10037796

## Citation

> US National Institutes of Health, RePORTER application 10037796, NVEADRC Administrative Core (AC) (1P20AG068053-01). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10037796. Licensed CC0.

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