# CSR&D Research Career Scientist Award Application

> **NIH VA IK6** · JAMES J PETERS VA  MEDICAL CENTER · 2021 · —

## Abstract

SUMMARY
Dr. Haghighi's research specialty is in medical epigenetics with applications to traumatic brain Injury (TBI),
depression, and suicidal behavior. These epigenetic studies involve how genes are differentially transcribed
and regulated, within human clinical and postmortem brain samples, providing a snapshot of potential
transcriptional regulatory abnormalities associated with disease neuropathology. Dr. Haghighi's clinical studies
show how environmental exposure affects the epigenome. Specifically, in her studies involving traumatic brain
injury, she investigates how response to repeated blast-exposure induces long-term transcriptional regulatory
changes resulting in symptoms of sleep disturbances, anxiety, cognitive deficits and depression and PTSD.
Additionally, she investigates how the role of stress, specifically chronic stress, induces epigenetic changes
associated with depression and suicide in the Veteran population.

## Key facts

- **NIH application ID:** 10041710
- **Project number:** 5IK6CX002074-02
- **Recipient organization:** JAMES J PETERS VA  MEDICAL CENTER
- **Principal Investigator:** FATEMEH G HAGHIGHI
- **Activity code:** IK6 (R01, R21, SBIR, etc.)
- **Funding institute:** VA
- **Fiscal year:** 2021
- **Award amount:** —
- **Award type:** 5
- **Project period:** 2019-10-01 → 2024-09-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10041710

## Citation

> US National Institutes of Health, RePORTER application 10041710, CSR&D Research Career Scientist Award Application (5IK6CX002074-02). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10041710. Licensed CC0.

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