# Improving Cardiac Rehabilitation outcomes through mobile case management (iCARE)

> **NIH NIH R01** · MAYO CLINIC ROCHESTER · 2020 · $540,159

## Abstract

PROJECT SUMMARY/ABSTRACT
Cardiovascular disease (CVD) is the leading cause of death in the world. Comprehensive cardiac rehabilitation
(CR) programs have repeatedly been shown to reduce morbidity and mortality while improving symptoms and
quality of life for patients living with this chronic disease. While referral rates to CR programs for patients
following a coronary event or procedure have slowly begun to increase in recent years, patient participation in
these programs has not. Further, adherence and completion of CR programs for those patients enrolled also
falls well short of target. There are a number of known barriers to participation in and completion of CR, which
contribute substantially the widening gap between CR referral, enrollment, and completion of CR.
The objective of this proposal is to determine the effectiveness of a mobile health (mHealth) remote case
management platform for increasing CR adherence, improving CVD risk factors, and improving patient-
centered outcomes. This prospective, randomized controlled trial of CR using a mHealth remote case
management platform compared to conventional center-based CR has been developed through interaction
with a number of key stakeholders including patients, clinical CR support staff, scientists, physicians, and
healthcare leaders. All non-surgical patients who have experienced a myocardial infarction, acute coronary
syndrome, percutaneous coronary intervention, have stable angina, or have heart failure will automatically be
referred to CR and be eligible to participate in this trial.
We anticipate that patients who utilize the mHealth remote case management platform will have improved
clinical outcomes compared to conventional center-based CR, as evidenced by increased adherence to CR
programming, improved CVD risk factors, and improved rehospitalizations/mortality.

## Key facts

- **NIH application ID:** 10046065
- **Project number:** 1R01NR018832-01A1
- **Recipient organization:** MAYO CLINIC ROCHESTER
- **Principal Investigator:** Thomas Patrick Olson
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $540,159
- **Award type:** 1
- **Project period:** 2020-09-14 → 2025-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10046065

## Citation

> US National Institutes of Health, RePORTER application 10046065, Improving Cardiac Rehabilitation outcomes through mobile case management (iCARE) (1R01NR018832-01A1). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10046065. Licensed CC0.

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