# Resource Core 3 - Teaching/Training/Dissemination Core (TTDC)

> **NIH NIH U19** · STANFORD UNIVERSITY · 2021 · $212,740

## Abstract

Resource Core 3 - Teaching/Training/Dissemination Core (TTDC)
 Leads: Maisie Lo PhD and Kristin Overton PhD
Summary
 The TTDC’s teaching mission specifically leverages our educational infrastructure for advancing the
application of modern neurotechnology methods in short (3-day) or extended-format (3-week) workshops. As
key papers are published, the specific methods are taught including 1) circuit optics (frame-projected
independent-fiber photometry during behavior, widefield cortical imaging during behavior, and single-cell all-
optical 2P interfacing (observation and control) during behavior) as well as 2) circuit molecular anatomy
(CLARITY/COLM: latest-generation CLARITY volume acquisition, quantification, and analysis across species;
INTRSECT/vCAPTURE: viral targeting for anatomically- and connectivity-specified cellular-resolution activity
visualization and causal control designed to take into account history of the cell (including past cellular activity
during behavior); and STARmap: species-independent tools for deep molecular phenotyping of circuit elements
naturally used during specific behaviors and linked to 3D positioning in tissue). Teaching methods are based on
our years of experience with teaching neuroscience technologies like optogenetics, as well as our familiarity with
some of the latest curriculum-structure ideas for practical engineering training-- which arise from U19 PI and
curriculum creator Karl Deisseroth’s experience as director of undergraduate education (including lab courses)
in Bioengineering at Stanford. The mission and scope of the technology cores (POC and PMAC) versus the
training core (TTDC) are well-separated. The technology cores, as described therein, will be engaged with
developing new advanced technology to advance the leading edge of optical and molecular anatomy methods
over the lifetime of the U19, while also ensuring that the U19 members have access to these new methodologies.
In contrast, the TTDC is tasked with dissemination of already-developed, more established, robust, and well-
validated, technologies to the broader NIH BRAIN community (as well as to any U19 members who will require
these foundational skills and technologies before advancing to the newer strategies).

## Key facts

- **NIH application ID:** 10047731
- **Project number:** 1U19NS118284-01
- **Recipient organization:** STANFORD UNIVERSITY
- **Principal Investigator:** Maisie KY Lo
- **Activity code:** U19 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $212,740
- **Award type:** 1
- **Project period:** 2021-09-17 → 2026-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10047731

## Citation

> US National Institutes of Health, RePORTER application 10047731, Resource Core 3 - Teaching/Training/Dissemination Core (TTDC) (1U19NS118284-01). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10047731. Licensed CC0.

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