# Latino Youths Coping with Discrimination: A Multi-Level Investigation in Micro- and Macro-Time > **NIH NIH R01** · MASSACHUSETTS GENERAL HOSPITAL · 2020 · $717,460 ## Abstract Project Summary Exposure to discrimination-related stressors (e.g., racial/ethnic discrimination, unfair treatment) continues to pose a public health challenge to minority populations as a social determinant of health. Although discrimination-related stressors have been consistently associated with poor mental health outcomes, there is a critical need to identify mechanisms and malleable risk/protective factors to integrate in the design of community and clinical interventions. The overall objective of this R01 application is to investigate mediators and moderators at multiple ecological (individual, family/peer and school/neighborhood levels) and time-scale (micro- and macro-time) levels in the link between discrimination-related stressors and mental health among 340 Mexican-origin youth. Guided by a socioecological, life course perspective, the proposed project has three specific aims: (1) determine within-person discrimination-related stressors that impact Mexican-American origin youth’s mental health outcomes as well as the mechanisms of action at both micro- and macro-time levels; (2) identify protective factors that could help youth to successfully cope with discrimination-related stressors and the conditions under which those protective factors work; and (3) elucidate the youth, parent, and neighborhood risk factors that moderate the link between discrimination-related stressors and mental health in youth. The project’s long-term goal is to improve the mental health of Mexican-origin youth by reducing the deleterious effects of racism, “othering,” and negative neighborhood interactions. The central hypothesis is that this link will be mediated by cognitive and/or affective mechanisms (i.e. anger, hypervigilance, emotion regulation, low social position as threats to self-worth) and moderated by coping resources (parental adaptation and racial socialization) and family, peer, and neighborhood supports, thus representing multiple ecological levels. Community-based collaboration will help ensure recruitment of the targeted sample of Mexican-origin adolescents, mothers, and fathers; the inclusion of fathers will be a valuable contribution to the literature, given the dearth of studies on Latinx fathers/stepfathers. Through the innovative integration of both yearly longitudinal (macro-time) and daily diary (micro-time) research design features, important questions about how mediating and moderating processes unfold over time will be addressed. The proposed analyses also reflect the multi-layered sociocultural niches occupied by Latinx adolescents by employing individual-level methods as well as dyadic (adolescent-mother; adolescent-father) and triadic (adolescent-mother-father) analyses to test key study hypotheses. Considering the current growth of Latinx immigrants, it is imperative to test a socioecological model of risk and resilience for Mexican-origin adolescents that is responsive to both their immediate context and the larger global fo... ## Key facts - **NIH application ID:** 10052270 - **Project number:** 1R01MD014737-01A1 - **Recipient organization:** MASSACHUSETTS GENERAL HOSPITAL - **Principal Investigator:** MARGARITA ALEGRIA - **Activity code:** R01 (R01, R21, SBIR, etc.) - **Funding institute:** NIH - **Fiscal year:** 2020 - **Award amount:** $717,460 - **Award type:** 1 - **Project period:** 2020-08-01 → 2025-02-28 ## Primary source NIH RePORTER: https://reporter.nih.gov/project-details/10052270 ## Citation > US National Institutes of Health, RePORTER application 10052270, Latino Youths Coping with Discrimination: A Multi-Level Investigation in Micro- and Macro-Time (1R01MD014737-01A1). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10052270. Licensed CC0. --- *[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*