# Optimizing PrEP Utilization among Alcohol and Other Drug (AOD) Using Women of Color

> **NIH NIH U34** · FLORIDA INTERNATIONAL UNIVERSITY · 2020 · $143,465

## Abstract

Project Summary
As we edge closer to the half century mark of the HIV epidemic, the disproportionate effect on women of color
in the U.S. continues to be jolting. Women overall have been at a disadvantage in the epidemic due to gender
differences and norms that shape biological, social and economic vulnerability. Racial and ethnic disparities
magnify the risk. Co-factors such as alcohol and other drug (AOD) use intersect and reinforce other
comorbidities. Living in a high prevalence area significantly hardens the risk and makes it tougher to
overcome. Options to help women stay HIV negative have been limited. However, this obstacle shifted several
years ago with FDA approval and CDC endorsement of oral pre-exposure prophylaxis (PrEP). Yet, the majority
of U.S. women do not know that PrEP can be a female-controlled strategy or that it applies to them—and
backup has not been forthcoming from providers or their communities. What is most disturbing, however, is the
absence of PrEP as an accessible strategy among women of color in high impact regions of the country. This
developmental U34 responds to RFA-AA-17-013, which prioritizes community based participatory research
(CBPR) to develop implementation models for women that address alcohol and HIV in high impact regions and
communities. The proposed study will produce an evidence- and CBPR-driven PrEP implementation
intervention to enhance uptake and optimize use among women of color in South Florida, which is currently the
highest impact region of the U.S. with HIV rates recently determined by the CDC to be the highest in the
nation. The study builds upon the team’s experience in alcohol/HIV intervention and CBPR in South Florida
and preliminary work with stakeholders from the greater Miami and Fort Lauderdale areas to develop a multi-
level PrEP intervention program for African American, Latina, and Haitian women who engage in risky sex and
AOD use. The study includes researchers from the Southern HIV and Alcohol Research Consortium (SHARC)
and will inform the design of target and comparison groups and other features of a U01 for further study within
the NIAAA CHAART Consortia. Guided by the social ecological framework, the study will: identify needs,
priorities, and community strengths and develop a PrEP continuum during a summit to engage stakeholders
(Aim 1); produce a replicable implementation program, including manuals, materials, instruments, and
procedures, through the formation of a Community Advisory and Advocacy Board (Aim 2); and conduct an
exploratory pilot among 120 multi-ethnic women of color in Broward and Miami-Dade counties to test fidelity,
feasibility and acceptability and measure PrEP uptake and adherence and retention in care over a 6 month
period. The study will utilize biomarkers in a subsample to compare with self-reports and pharmacy refill
measures. It will be among the first to develop a PrEP intervention in the South for women of color, and is thus
in line with the speci...

## Key facts

- **NIH application ID:** 10053581
- **Project number:** 3U34AA026219-03S1
- **Recipient organization:** FLORIDA INTERNATIONAL UNIVERSITY
- **Principal Investigator:** JESSY G. DEVIEUX
- **Activity code:** U34 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $143,465
- **Award type:** 3
- **Project period:** 2019-11-14 → 2021-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10053581

## Citation

> US National Institutes of Health, RePORTER application 10053581, Optimizing PrEP Utilization among Alcohol and Other Drug (AOD) Using Women of Color (3U34AA026219-03S1). Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/grant/nih/10053581. Licensed CC0.

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