# Research and Mentorship in Medical Decision Making for Chronic Diseases of Older Adults

> **NIH NIH K24** · UNIVERSITY OF CHICAGO · 2020 · $116,513

## Abstract

PROJECT ABSTRACT: Medical decisions for many chronic diseases such as diabetes are becoming more
complex as the number of available therapies expand and as we learn how risk factor targets and treatments
may need to be individualized based on a patient's clinical characteristics, genetic profiles, treatment
preferences, and social circumstances. To strengthen training and research in medical decision making in the
study of chronic diseases of older adults, Dr. Elbert Huang, Professor of Medicine at the University of Chicago,
is submitting this K24 renewal proposal. The University of Chicago is an ideal environment for this program
because of its well-established clinical research programs, history of interdisciplinary collaboration, and
significant strengths in the social sciences. The overall goal of the program is to support young investigators
who are studying medical decision making in older adults living with individual or multiple chronic diseases.
Trainees of the program will have access to cohort studies of older adults (Kaiser Permanente Northern
California Diabetes Registry, the National Social Life Health and Aging Project, national Medicaid and
Medicare Claims), support for the construction and evaluation of simulation models of chronic diseases,
guidance for developing decision support interventions, and facilitated access to the UChicago Practice-Based
Research Network. In his own research in geriatric diabetes, Dr. Huang will pursue the following aims: 1)
advance the study of variation in diabetes onset, complications and treatment response in observational
studies; 2) advance the development of simulation models of diabetes complications; and 3) advance the
development of diabetes decision support for personalizing care for older adults. In two ongoing observational
studies (R01 AG060756, R01 AG063391), Dr. Huang will explore population-level variation in the onset of
diabetes and its complications as well as variation in response to achieved glucose targets and treatments. As
part of Aim 2, Dr. Huang is part of an investigative team led by his mentee, Dr. Neda Laiteerapong (R01
MD013420) developing a new simulation model of diabetes complications using multi-ethnic data from the
Kaiser Registry. This model will be comprised of a series of individual outcome prediction models
(cardiovascular events, hypoglycemia, dementia, mortality) that interwoven together. Under Aim 3, Dr. Huang
will first complete evaluation of a trial of a decision support tool (My Diabetes GOAL) created during his initial
K24. The tool, embedded within the electronic medical record, is designed to engage patients in personalized
goal setting and disease management with the support of a nurse. He will also develop an updated
stakeholder-informed diabetes decision support intervention for personalized care for older adults, addressing
both goal setting and treatment selection. This K24 award will allow Dr. Huang to strengthen his mentorship
program in medical ...

## Key facts

- **NIH application ID:** 10055247
- **Project number:** 2K24AG069080-06
- **Recipient organization:** UNIVERSITY OF CHICAGO
- **Principal Investigator:** ELBERT S. HUANG
- **Activity code:** K24 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $116,513
- **Award type:** 2
- **Project period:** 2020-09-01 → 2025-05-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10055247

## Citation

> US National Institutes of Health, RePORTER application 10055247, Research and Mentorship in Medical Decision Making for Chronic Diseases of Older Adults (2K24AG069080-06). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10055247. Licensed CC0.

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