# Shared Resource Core

> **NIH NIH P50** · MEDICAL UNIVERSITY OF SOUTH CAROLINA · 2021 · $428,819

## Abstract

SUMMARY
The Shared Resource Core provides centralized resources and services that are tailored to the research needs
of investigators in the Charleston Alcohol Research Center (ARC). In doing so, the Shared Resource Core
continues to serve the critical role of promoting scientific integration, increasing efficient use of resources, and
facilitating use of high quality contemporary technological and investigatory approaches that, collectively, are
key to supporting the dynamic research environment fostered by the ARC.
The Shared Resource Core is comprised of the Animal Core, the Clinical Intake and Assessment Core, and the
Biostatistics Core. The Animal Core provides basic research projects and pilot projects with animals treated in
a well-validated and established mouse model of alcohol dependence that involves repeated cycles of chronic
intermittent ethanol (CIE) exposure. The Animal Core also will validate molecular tools (e.g., viruses for targeting
cell-specific chemo/opto-genetic and fiber photometry manipulations) for effectiveness prior to their use in
research projects. The Clinical Intake and Assessment Core will provide centralized advertisement and
recruitment efforts, perform initial screening of potential study participants, conduct clinical/lab assessments to
determine suitability for enrollment in specific clinical projects and pilot projects, and provide general medical
oversight for clinical studies in the Center. The Biostatistics Core will continue to provide data management
and statistical service to both basic and clinical research projects and pilots in the ARC. This includes assisting
in study design development, performing power analyses at the front end of the projects, construction of
appropriate databases, conducting analyses utilizing various contemporary statistical approaches, and assisting
in preparation of manuscripts and presentations for dissemination of study results.
By centralizing these vital scientific functions, the Core avoids duplication of efforts, increases efficient use of
resources, facilitates use of state-of-the-art research approaches and techniques, and improves quality control
through oversight of centralized functions - all contributing to maximizing productivity in the ARC. Overall, the
Shared Resource Core plays a pivotal role in enhancing integration and cohesion of ARC research activities, as
well as stimulating and supporting the vibrant alcohol research and training environment at MUSC.

## Key facts

- **NIH application ID:** 10055952
- **Project number:** 2P50AA010761-26
- **Recipient organization:** MEDICAL UNIVERSITY OF SOUTH CAROLINA
- **Principal Investigator:** HOWARD C. BECKER
- **Activity code:** P50 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $428,819
- **Award type:** 2
- **Project period:** 1996-12-01 → 2025-12-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10055952

## Citation

> US National Institutes of Health, RePORTER application 10055952, Shared Resource Core (2P50AA010761-26). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10055952. Licensed CC0.

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