# International Herpesvirus Workshop

> **NIH NIH R13** · OREGON HEALTH & SCIENCE UNIVERSITY · 2021 · $10,000

## Abstract

Project Summary
This proposal requests funds to be used to support travel and registration fees for postdoctoral fellows and
graduate students to attend the 45th International Herpesvirus Workshop (IHW) in Berlin, Germany. The IHW is
the major annual meeting for scientists studying all the herpesviruses and is very well established in its 45th
year. This meeting has been very successful, in part, because of the enthusiastic participation of the world’s
leading herpesvirus researchers. The strength of the Workshop rests on the cross-fertilization that results from
comparison of different herpesviruses, different approaches to key questions and on the support and
participation of leading researchers in the field, most significantly including promising young investigators and
students in training. Moreover, the forum is truly international, with broad-based world-wide attendance. The
medical importance of this meeting is clearly indicated from the wide variety of diseases caused by the now-
recognized eight human herpesviruses. These include skin and eye ulcerations (HSV-1), genital lesions (HSV-
2), meningitis and encephalitis (HSV-1 and HSV-2), infectious mononucleosis (EBV), chicken pox and shingles
(VZV). CMV is a major cause of birth defects including mental retardation, blindness and deafness due to
congenital transmission but also a significant opportunistic pathogen in AIDS patients and organ transplant
recipients. In addition, CMV has been implicated as a pathogenic contributor in the development of
atherosclerosis. Cancer has also been associated with herpesvirus infections. EBV is associated with Burkitt’s
lymphoma, other B cell neoplasias and nasopharyngeal carcinoma. The most recent human herpesvirus
discovered (HHV-8 or KSHV) is associated with Kaposi’s sarcoma in AIDS patients and other
immunosuppressed persons in other groups. All of the herpesviruses persist for life and therefore pose
significant problems in the treatment of immune-compromised individuals. Diseases caused by reactivation of
most human herpesviruses are a significant cause of morbidity and mortality in various immune patient
populations. Workshop sessions will take an interdisciplinary approach to the following topics: virus structure,
mechanism of virus entry and cell-cell spread, membrane proteins, pathogenesis and latency, DNA replication,
vaccination and the immune response, transcriptional control, regulation of gene expression, chemotherapeutic
targets, and virus gene therapy.

## Key facts

- **NIH application ID:** 10057653
- **Project number:** 1R13AI154555-01
- **Recipient organization:** OREGON HEALTH & SCIENCE UNIVERSITY
- **Principal Investigator:** JAY A NELSON
- **Activity code:** R13 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $10,000
- **Award type:** 1
- **Project period:** 2021-07-01 → 2022-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10057653

## Citation

> US National Institutes of Health, RePORTER application 10057653, International Herpesvirus Workshop (1R13AI154555-01). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10057653. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*