# Core 02: Cell Manipulation Core Facility

> **NIH NIH P30** · DANA-FARBER CANCER INST · 2021 · $491,729

## Abstract

Cell Manipulation Shared Resource
Project Summary / Abstract
The mission of the Cell Manipulation Core is to produce safe and effective cellular components for patients
enrolled in novel therapeutic clinical research protocols. In this context, the Core supports primarily
translational research and works closely with many laboratory investigators in the Cancer Immunology
Program as well as with clinical investigators in disease-focused Programs within DF/HCC. These DF/HCC
investigators work in diverse areas including hematopoietic stem cell transplantation, cancer vaccines, and
adoptive cellular therapy of cancer. All procedures are performed according to current Good Manufacturing
Practices (cGMPs) for cell and tissue processing. Regulations and standards have been developed by the
FDA's Center for Biologics Evaluation and Research (CBER), the American Association of Blood Banks
(AABB), and the Foundation for the Accreditation of Cellular Therapy (FACT). The policies and procedures
established in the facility comply with these standards and regulations, ensuring the production of safe,
effective components for clinical use. Cellular products processed by the Core are provided in the context of
clinical research protocols that have been reviewed and approved by the DF/HCC Scientific Review Committee
and Institutional Review Board. Together with adherence to cGMPs, the requirement that extensive cell
processing is only provided for patients enrolled on approved clinical research protocols ensures that this core
facility provides a unique service to DF/HCC Research Programs and Members.

## Key facts

- **NIH application ID:** 10062884
- **Project number:** 5P30CA006516-56
- **Recipient organization:** DANA-FARBER CANCER INST
- **Principal Investigator:** JEROME RITZ
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $491,729
- **Award type:** 5
- **Project period:** 1997-03-10 → 2021-11-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10062884

## Citation

> US National Institutes of Health, RePORTER application 10062884, Core 02: Cell Manipulation Core Facility (5P30CA006516-56). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10062884. Licensed CC0.

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