# Shared Resource 05: Collaborative Functional Genomics

> **NIH NIH P30** · DANA-FARBER CANCER INST · 2021 · $149,695

## Abstract

Collaborative Functional Genomics Shared Resource
Project Summary / Abstract
Understanding the basic biological mechanisms that underlie the development and progression of cancer is
fundamental to finding better approaches to cancer prevention and treatment. Loss-of-function genetic
approaches, such as high-throughput RNA interference (RNAi) and CRISPR/Cas9, as well as gain-of-function
approaches such as open reading frame (ORF) over-expression and CRISPR-activation (CRISPR-a) provide
cutting-edge strategies to identify new cancer-related genes and pathways. The Collaborative Functional
Genomics Core offers a single portal through which DF/HCC members gain access to technologies, reagents,
services, and scientific consultation. The Core mission is to support the widest possible range of functional
genomics screening projects; rapidly disseminate information about new functional genomics approaches; and
help researchers navigate from concept and assay development to high-throughput screening, analysis, and
validation.

## Key facts

- **NIH application ID:** 10062890
- **Project number:** 5P30CA006516-56
- **Recipient organization:** DANA-FARBER CANCER INST
- **Principal Investigator:** STEPHANIE E MOHR
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $149,695
- **Award type:** 5
- **Project period:** 1997-03-10 → 2021-11-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10062890

## Citation

> US National Institutes of Health, RePORTER application 10062890, Shared Resource 05: Collaborative Functional Genomics (5P30CA006516-56). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10062890. Licensed CC0.

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