# Program 52: Kidney Cancer

> **NIH NIH P30** · DANA-FARBER CANCER INST · 2021 · $76,748

## Abstract

Kidney Cancer Program
Project Summary / Abstract
The Kidney Cancer Program performs innovative basic research into the molecular basis of kidney tumors.
Scientific efforts within the current funding period have focused on identifying meaningful biomarkers for early
detection and prognosis, underlying mechanisms of disease biology and novel therapeutic targets for the
various kidney cancer populations, and improved preclinical models for preliminary validation of these findings.
The specific aims of the program are to 1) Identify and validate novel targets in kidney cancer, and establish
pre-clinical models for testing new agents; 2) Identify molecular and biologic predictors of response and toxicity
to therapy; 3) Leverage Program and SPORE infrastructure to facilitate drug and device development; and 4)
Identify factors that increase the risk, predict the development and recurrence of kidney cancer. The program
has 38 members, representing seven DF/HCC institutions and 8 academic departments. In 2014 peer-
reviewed grant funding attributed to the Program was $1.3 million in total costs from the NCI and $1.2 million
from other sponsors. During the current funding period, Kidney Cancer Program members published 742
cancer-relevant papers. Of these 36% were inter-institutional, 14% were intra-programmatic, and 51% were
inter-programmatic collaborations between two or more DF/HCC members. Overall, when counted once, 27%
of DF/HCC publications were inter-programmatic collaborations.

## Key facts

- **NIH application ID:** 10062946
- **Project number:** 5P30CA006516-56
- **Recipient organization:** DANA-FARBER CANCER INST
- **Principal Investigator:** David McDermott
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $76,748
- **Award type:** 5
- **Project period:** 1997-03-10 → 2021-11-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10062946

## Citation

> US National Institutes of Health, RePORTER application 10062946, Program 52: Kidney Cancer (5P30CA006516-56). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10062946. Licensed CC0.

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