# Program 9: Cancer Genetics

> **NIH NIH P30** · DANA-FARBER CANCER INST · 2020 · $2,948

## Abstract

Cancer Genetics Program
Project Summary / Abstract
The overall mission of the Cancer Genetics Program is to expand our understanding of the genetic basis of
cancer development and to use this knowledge to improve the care of cancer patients. To advance this
mission, the Program has assembled a large and vibrant membership, including investigators with a broad
range of scientific interests in all major aspects of cancer genetics. Particular areas of focus include: 1) cancer
gene discovery and functional characterization (in both human cancers and model organisms), 2) technology
development and application (e.g., massively parallel sequencing, emerging genomic technologies, and single
cell analyses), 3) computational analysis (e.g., algorithm development, bioinformatics methods, and genome
annotation approaches), 4) genetic and molecular studies of cancer progenitor cells, 5) analysis of
mechanisms of cancer targeted therapy resistance, 6) clinical cancer genetics, including risk counseling, and
7) delivery of state-of-the-art CLIA-certified testing of both cancer gene panels and of whole exomes for cancer
precision medicine. The program has 111 members, representing seven DF/HCC institutions and 14 academic
departments. In 2014 peer-reviewed grant funding attributed to the Program was $8.2 million in total costs from
the NCI and $25.1 million from other sponsors. During the current funding period, Cancer Genetics Program
members published 2,332 cancer-relevant papers. Of these 31% were inter-institutional, 15% were intra-
programmatic, and 48% were inter-programmatic collaborations between two or more DF/HCC members.
Overall, when counted once, 27% of DF/HCC publications were inter-programmatic collaborations.

## Key facts

- **NIH application ID:** 10063165
- **Project number:** 3P30CA006516-55S4
- **Recipient organization:** DANA-FARBER CANCER INST
- **Principal Investigator:** David J. Kwiatkowski
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $2,948
- **Award type:** 3
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10063165

## Citation

> US National Institutes of Health, RePORTER application 10063165, Program 9: Cancer Genetics (3P30CA006516-55S4). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10063165. Licensed CC0.

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