# West Virginia Pediatric Clinical Trials Network-2

> **NIH NIH UG1** · WEST VIRGINIA UNIVERSITY · 2020 · $417,930

## Abstract

Abstract
West Virginia (WV) bears long-standing physical, psychosocial and fiscal characteristics, including the opioid
crisis, limited resources and a restricted economy, that have significantly impacted the health of its residents.
The West Virginia Pediatric Clinical Trials Network (WVPCTN), as a Clinical Site of the ECHO IDeA States PCTN
(ISPCTN), has catalyzed emerging solutions to address some of these burdens by fulfilling its mission.
Specifically, the mission of the WVPCTN has been two-fold - bringing clinical trials to our underserved population,
and building professional capacity for clinical research. Our WVU site has been well positioned to be a successful
Clinical Site due to a combination of structural and human resources that were already in place when the ISPCTN
was initiated in 2016, and the background and expertise of the three PIs – Drs. Saul, Pyles and Cottrell. The
addition of the funds and resources provided by ISPCTN led to an acceleration of WVUs capacity to actively
participate in clinical trials by allowing us to create a dedicated Pediatric Research Unit (PRU) and introduce a
group of junior, less experienced clinical trial investigators, into both ISPCTN and non-ISPCTN trials. The
effectiveness of this approach has been demonstrated through an increase in faculty participation in ISPCTN
activities, a strong recruitment record, and an increase in the number of non-ISPCTN Pediatric trials at WVU.
The WVPCTN is now actively growing an experienced investigator pool and a group of mentee investigators, all
enhanced by the resources and expertise of the West Virginia Clinical Translational Science Institute (WVCTSI).
These features and resources, together with strong and sustained partnerships throughout the state, and the
multiple environmentally related conditions of our citizens, continue to uniquely position us to be successful as
an ISPCTN Clinical Site and work to propose new trials for the network. This proposal for WVPCTN-2 will further
add to a long-standing commitment to Pediatric-focused initiatives across the state. When funded, it will continue
to position us to fully leverage additional funds that support Pediatric research infrastructure and provide access
to cutting edge trials, both of which will positively impact the health of the children of WV.

## Key facts

- **NIH application ID:** 10064509
- **Project number:** 2UG1OD030016-02
- **Recipient organization:** WEST VIRGINIA UNIVERSITY
- **Principal Investigator:** LESLEY A COTTRELL
- **Activity code:** UG1 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $417,930
- **Award type:** 2
- **Project period:** 2020-09-01 → 2025-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10064509

## Citation

> US National Institutes of Health, RePORTER application 10064509, West Virginia Pediatric Clinical Trials Network-2 (2UG1OD030016-02). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10064509. Licensed CC0.

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