# Epidemiological and Statistical Methods Core (ESC)

> **NIH NIH P01** · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · 2020 · $440,062

## Abstract

PROJECT SUMMARY
The Pediatric HIV/AIDS Cohort Study (PHACS) is a large-scale multi-site network with multiple observational
studies aimed to evaluate the long-term effectiveness and safety of population-based interventions to prevent
perinatal HIV transmission and HIV progression and inform HIV remission/cure strategies. The PHACS
Research Projects have generated and will continue to gather data on health determinants from various
sources and via diverse methods including clinical, social, genomic, microbiome, and imaging data. A multitude
of concept sheets and sub-studies will therefore be proposed requiring specialized epidemiological and
statistical expertise, ranging from efficient study design, causal inference methodology, deep learning
algorithms, bioinformatics, and integrative microbiome informatics, to inform data analyses that will be
conducted by the PHACS Data Resources Core (DRC). As we continue to add to our extensive PHACS
database, new and challenging problems are likely to arise that may necessitate the development of innovative
study designs and analytic methods, particularly in the fields of pediatric and perinatal epidemiology. Ongoing
training will be required on these and other methodological innovations for PHACS epidemiologists and
statisticians. Continuing education on fundamental epidemiological and statistical principles will also be
required for all PHACS investigators in order to conduct effective collaborative research.
To address these needs and promote valid and efficient pediatric and perinatal HIV research within the
Research Projects and any focused Emerging Research Pilots, the PHACS Epidemiological and Statistical
Methods Core (ESC) has been established to: (1) provide specialized epidemiological and statistical services,
support, and resources; (2) promote the development and application of novel epidemiological and statistical
methods; and (3) support continuing education in epidemiological and statistical methods through in-person or
web-based training and mentorship of early career investigators.

## Key facts

- **NIH application ID:** 10065448
- **Project number:** 1P01HD103133-01
- **Recipient organization:** HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH
- **Principal Investigator:** KUNJAL PATEL
- **Activity code:** P01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $440,062
- **Award type:** 1
- **Project period:** 2020-09-18 → 2025-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10065448

## Citation

> US National Institutes of Health, RePORTER application 10065448, Epidemiological and Statistical Methods Core (ESC) (1P01HD103133-01). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10065448. Licensed CC0.

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