# METABOLOME ANALYSES OF SALIVA SAMPLES FROM HIV+ PATIENTS ON cART

> **NIH NIH R01** · CASE WESTERN RESERVE UNIVERSITY · 2020 · $170,505

## Abstract

ABSTRACT
Our parent grant has been awarded for studying HIV associated human oral mucosal immune dysfunction using
in vitro HIV tonsil cell system (Aim 1-parent grant) and HIV+ patient derived cells (Aim 2-parent grant). Our
current proposal involves a new aim where we hypothesize that oral immune cell dysregulation that we observed
in HIV+ patients might correlate with metabolite changes in saliva derived from HIV+ patients. This sub-project,
in the context of the parent grant will lead to new ways of thinking about oral inflammation in HIV+ individuals,
and aid in generating novel therapeutic strategies to manage HIV mediated chronic inflammation and cancer.

## Key facts

- **NIH application ID:** 10067125
- **Project number:** 3R01DE026923-04S1
- **Recipient organization:** CASE WESTERN RESERVE UNIVERSITY
- **Principal Investigator:** Pushpa Pandiyan
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $170,505
- **Award type:** 3
- **Project period:** 2017-04-01 → 2022-04-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10067125

## Citation

> US National Institutes of Health, RePORTER application 10067125, METABOLOME ANALYSES OF SALIVA SAMPLES FROM HIV+ PATIENTS ON cART (3R01DE026923-04S1). Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/grant/nih/10067125. Licensed CC0.

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