# DAMPs Across the Tree of Life Inducing Innate Immunity

> **NIH NIH R13** · KEYSTONE SYMPOSIA · 2020 · $10,000

## Abstract

ABSTRACT
Support is requested for a Keystone Symposia conference entitled DAMPs Across the Tree of Life Inducing
Innate Immunity organized by Drs. Seung-Yong Seong, Zhijian Chen, Walter G. Land and Polly Matzinger.
The conference will be held in Republic of Korea from September 21 - 25, 2020.
Injury-induced Damage Associated Molecular Patterns (DAMPs) are beginning to shape modern medicine in
the field of both diagnostics and therapeutics. For example, DAMPS are already recognized to be major
contributors to rejection in the field of transplantation, and efforts are underway to target them. Research is
showing that they can also contribute to rejection of tumors, for example with immunogenic cell death, and
efforts are underway to stimulate them for cancer eradication. With their use, new vaccination modalities will
be developed against viral infections, including HIV and ZIKA virus. Further, DAMPs-based innovative
diagnostic methods and new therapeutic strategies will soon improve survival rates of critically ill patients, such
as those who have undergone major trauma. Due to its involvement in autoimmune diseases, chronic
inflammatory diseases, and allergic diseases, as well as plant resistance to predators, initiation of innate
immune responses by DAMPs is currently a thriving research area. It covers both medical and agricultural
fields. The goal of this conference is to convene internationally renowned experts from academia, biotech and
pharma, in fields reflecting the diversity listed above, to present and discuss their latest findings in DAMPs
research and applications.

## Key facts

- **NIH application ID:** 10070025
- **Project number:** 1R13AI154652-01
- **Recipient organization:** KEYSTONE SYMPOSIA
- **Principal Investigator:** Thale Cross Jarvis
- **Activity code:** R13 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $10,000
- **Award type:** 1
- **Project period:** 2020-09-01 → 2021-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10070025

## Citation

> US National Institutes of Health, RePORTER application 10070025, DAMPs Across the Tree of Life Inducing Innate Immunity (1R13AI154652-01). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10070025. Licensed CC0.

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