# Autophagy

> **NIH NIH R13** · KEYSTONE SYMPOSIA · 2020 · $4,000

## Abstract

ABSTRACT
Support is requested for a Keystone Symposia conference entitled Autophagy organized by Drs. Patricia Boya,
Felix Randow and Masaaki Komatsu. The conference will be held in Killarney, Ireland from October 4-8, 2021.
Autophagy is an intracellular pathway for degradation that allows for the recycling of cellular components inside
lysosomes to sustain tissue homeostasis. Countless effort has been devoted to help unravel the molecular
mechanisms that regulate this pathway, but many questions remain unresolved. Therefore, this conference
program gathers an interdisciplinary group of scientists to address the current and future challenges in the field
such as discussions on the existence of non-canonical forms of the pathway and how selectivity is achieved.
This conference also addresses the minimal requirements to generate functional autophagosomes and the
molecular bases of autophagy regulation. One of the major themes of this conference is a session which
reviews how model systems such as plants, worms and mice help to unravel the physiological roles of this
essential pathway and why this research can also be applied to find new therapies for human diseases. For
example, while it is now clear that many human pathologies have alterations in autophagy, how scientists
could potentially manipulate the pathway in vivo is a major challenge that will be addressed at this conference.
Finally, this conference provides a unique frame to display the current research and future challenges of the
field during physiological and pathological conditions.

## Key facts

- **NIH application ID:** 10070551
- **Project number:** 1R13CA254442-01
- **Recipient organization:** KEYSTONE SYMPOSIA
- **Principal Investigator:** Thale Cross Jarvis
- **Activity code:** R13 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $4,000
- **Award type:** 1
- **Project period:** 2020-09-01 → 2021-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10070551

## Citation

> US National Institutes of Health, RePORTER application 10070551, Autophagy (1R13CA254442-01). Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/grant/nih/10070551. Licensed CC0.

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