# A Symposium on Nutrition State of Science for Dementia Prevention

> **NIH NIH R13** · UNIVERSITY OF SOUTHERN CALIFORNIA · 2020 · $50,000

## Abstract

Abstract
Overwhelming evidence from past nutrition clinical trials using interventions based on diets or
over-the-counter supplements indicate no reduction in the risk of cognitive decline. A recent
systematic review by the Lancet Commission, however, identified that about 30% of dementia
can be prevented by lifestyle modifications targeting chronic diseases such as diabetes, obesity
and hypertension and including dietary interventions. Critical to the mission of NIA will be a new
generation of nutrition studies with unique designs that can address this gap to help move the
field forward. The field is missing a roadmap to assist with translating quality nutrition science
into effective clinical trials and ultimately guide clinical recommendations. This symposium will
bring together leading experts in nutrition science, epidemiology and clinical trial design to
discuss a path to integrate new directions, including the application of omics technologies and
personalized approaches, imaging, nutrition assessment tools, modeling and other areas of
relevance to nutrition research and dementia prevention. The symposium is expected to layout
a framework for future areas of research in nutrition science by producing an expert
opinion paper that addresses the current state of science. Leveraging planning resources
from the Alzheimer’s Association, we plan this symposium on July 9th, 2021, preceding AAIC
2021 in Boston. We plan to reach out to ISTAAT members and expect around 300 scientists
from various disciplines related to dementia to attend this symposium. The program will be
planned during the year preceding the symposium through a series of meetings and
conference calls. This symposium will then provide a platform to engage the speakers
and attendees in moderated discussions and create expert recommendations. We expect
to (1) highlight how novel trial methodologies applicable to nutrition science can inform
future clinical trials (2) to provide guidance on relevant regulatory pathways and (3) identify
funding priorities. Moreover, the symposium will address the very limited diversity among
the current group of active nutrition trial investigators, nutrition in minorities, and how
health disparities impact the current nutrition state of science. Success of this program
will be evaluated based on participation level, diversity in attendance, engagement of
participants and publication of an expert opinion paper in a timely manner.

## Key facts

- **NIH application ID:** 10070866
- **Project number:** 1R13AG069386-01
- **Recipient organization:** UNIVERSITY OF SOUTHERN CALIFORNIA
- **Principal Investigator:** Hussein N Yassine
- **Activity code:** R13 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $50,000
- **Award type:** 1
- **Project period:** 2020-08-15 → 2022-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10070866

## Citation

> US National Institutes of Health, RePORTER application 10070866, A Symposium on Nutrition State of Science for Dementia Prevention (1R13AG069386-01). Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/grant/nih/10070866. Licensed CC0.

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