# Mitochondria, Metabolism and Heart

> **NIH NIH R13** · KEYSTONE SYMPOSIA · 2020 · $15,900

## Abstract

ABSTRACT
Support is requested for a Keystone Symposia conference entitled Mitochondria, Metabolism and Heart
organized by Drs. Elizabeth Murphy and Zoltan P. Arany. The conference will be held in Santa Fe, New
Mexico from January 14-18, 2021.
It is well known that mitochondria are the powerhouse of the cell and are responsible for generating ATP via
oxidative metabolism and electron transport. Mitochondrial transporters regulate mitochondrial calcium levels
which in turn are important in regulating cell metabolism and death. However, alterations in mitochondrial
function and metabolism have been shown to be important regulators of cardiovascular disease such as heart
failure. Despite the importance of mitochondria in health and disease, the identity of many ion transporters is
still unknown. In particular, the identity of the mitochondrial permeability pore that regulates cell death is still
debated. In addition, the links between mitochondrial dynamics and mitochondrial metabolism and cell death
are poorly understood. Therefore, this conference will emphasize experts using novel approaches such as
high-resolution imaging techniques, metabolomics, proteomics and systems biology to elucidate mechanisms
by which mitochondrial transporters and mitochondrial dynamics regulate metabolism, death and disease.
Finally, this conference is being paired with a Keystone Symposium on Heart Failure: Mechanisms and
Therapies. This pairing will include two joint sessions will focus on mitochondrial function and metabolism,
respectively.

## Key facts

- **NIH application ID:** 10071044
- **Project number:** 1R13HL154801-01
- **Recipient organization:** KEYSTONE SYMPOSIA
- **Principal Investigator:** Thale Cross Jarvis
- **Activity code:** R13 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $15,900
- **Award type:** 1
- **Project period:** 2020-09-01 → 2023-08-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10071044

## Citation

> US National Institutes of Health, RePORTER application 10071044, Mitochondria, Metabolism and Heart (1R13HL154801-01). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10071044. Licensed CC0.

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