# Methods Core

> **NIH NIH P50** · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · 2021 · $418,820

## Abstract

PROJECT SUMMARY – METHODS CORE
The OPAL Center's Methods Core will constitute its scientific infrastructure and its source of innovative
research momentum. We have designed the Core to be both responsive and generative; its resources will be
available to collaborators working on current or future projects related to our theme, and its membership will
actively chart needed areas of investigation and new methodologies. The Methods Core will pursue the
following specific aims:
Aim 1. Cultivate innovative research on treatments and services for schizophrenia that optimizes their
effectiveness in real-world clinical settings and readiness for broad deployment. With our extensive experience
as State agency collaborators seeking practice improvements, we are well aware of the limitations of traditional
research methods in addressing the unresolved barriers to recovery from psychosis and we are enthusiastic
about the potential of the Methods Core to create innovative, field-ready interventions that are important to
policy makers.
Aim 2. Support the work of OPAL projects and pilot studies by offering perspectives and skills from multiple
disciplines, and offer ideas and assistance to ensure productive use of OPAL resources.
The Methods Core will be comprised of several Units, each with a designated leader. These will include: 1)
quantitative methods (biostatistics, data management, and research design); 2) qualitative methods; 3) clinical
assessment and training; 4) health economics; 5) technology/mHealth; and 6) ethics and human subjects. The
Methods Core will respond to requests from the Administrative Core, especially with regard to evaluation of
Center activities, or when the Administrative Core needs direction in solicitation or review of pilot study
proposals.
Aim 3. Challenge students and early stage investigators to build skills and experience in critically needed
transdisciplinary areas of study, and provide on-going feedback on their work and career trajectories.

## Key facts

- **NIH application ID:** 10077405
- **Project number:** 5P50MH115843-04
- **Recipient organization:** NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC
- **Principal Investigator:** Melanie M Wall
- **Activity code:** P50 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $418,820
- **Award type:** 5
- **Project period:** 2018-04-01 → 2023-06-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10077405

## Citation

> US National Institutes of Health, RePORTER application 10077405, Methods Core (5P50MH115843-04). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10077405. Licensed CC0.

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