# Large Scale Cortical Laminar Recordings: Novel Instrumentation

> **NIH NIH R01** · RHODE ISLAND HOSPITAL · 2020 · $80,933

## Abstract

SUMMARY
We have successfully designed and fabricated the backPack drive for spine recordings in awake mice
(AIM I), and fully developed a novel behavioral model AIM II (see Y1 Progress Report and Black et
al.). In this SUPPLEMENTAL APPLICATION, we propose new experiments to elucidate the laminar
organization of low-frequency oscillations in SI at a much higher level of cellular localization than
originally sought. These new experiments will augment the overall impact of our project by localizing
oscillations in SI to specific lamina and correlating oscillations with thalamic single-unit firing in the
context of ecologically-relevant and ultra-fast nociceptive behavior. They will also generate high
dimensional neural data at multiple scales (single units, LFP) which will be available to other
investigators upon request.

## Key facts

- **NIH application ID:** 10078368
- **Project number:** 3R01NS108414-02S1
- **Recipient organization:** RHODE ISLAND HOSPITAL
- **Principal Investigator:** David Allenson Borton
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $80,933
- **Award type:** 3
- **Project period:** 2020-04-01 → 2020-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10078368

## Citation

> US National Institutes of Health, RePORTER application 10078368, Large Scale Cortical Laminar Recordings: Novel Instrumentation (3R01NS108414-02S1). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10078368. Licensed CC0.

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