# JHU Center for Neuroscience Research

> **NIH NIH P30** · JOHNS HOPKINS UNIVERSITY · 2020 · $155,563

## Abstract

SUMMARY: JHU Center for Neuroscience Research
In this revised competitive renewal of our “JHU Center for Neuroscience Research” NINDS P30 center grant,
we propose to both maintain and expand two of the Scientific Core facilities at the Johns Hopkins University
School of Medicine (JHU SOM) that have anchored this Center for the past 10 years: the Multiphoton
Imaging (MPI) Core and the Murine Mutagenesis Core (MMC; formally “ES Cell Engineering Core”). These
Scientific Cores currently provide critical research capabilities and resources that are impractical for
neuroscience investigators to provide on their own but that greatly enhance efforts of individual research
programs. The experimental opportunities and technical services offered by these Cores complement, but do
not duplicate, other facilities available to NINDS-funded investigators at JHU SOM. Use of Center Cores will
continue to benefit the 12 NINDS-funded research programs that constitute the Primary Center Investigators of
this Center, and also other NINDS-funded and non-NINDS-funded investigators at JHU SOM. The research
programs of the Primary Center Investigators address a wide range of significant unsolved questions central to
the NINDS mission. These include basic neuroscience investigation into excitatory synapse dynamics and
function, the organization of hippocampal place cell circuitry, definition of cortical circuits underlying
somatosensation, establishment of local circuitry during adult neurogenesis, cellular and molecular
mechanisms of pain and itch, and Ca++ signaling in Na channel regulation. Clinically relevant work
encompasses the genetics and molecular underpinnings of stroke, Parkinson's Disease, amyotrophic lateral
sclerosis, autism spectrum disorders, and sleep. The unique capabilities of Center Cores will continue to serve
as a crucial resource for NINDS-funded investigators at JHU by extending the research capabilities of
individual investigators and by serving as a focal point for dissemination and practical training in state-of-the art
research approaches. Through these efforts, the JHU Center for Neuroscience Research will help establish
new strategies for studying brain function in health and disease that will benefit the broader neuroscience
community.

## Key facts

- **NIH application ID:** 10079305
- **Project number:** 3P30NS050274-14S1
- **Recipient organization:** JOHNS HOPKINS UNIVERSITY
- **Principal Investigator:** ALEX L KOLODKIN
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $155,563
- **Award type:** 3
- **Project period:** 2005-09-01 → 2021-04-30

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10079305

## Citation

> US National Institutes of Health, RePORTER application 10079305, JHU Center for Neuroscience Research (3P30NS050274-14S1). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10079305. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*