# An Economical Point-of-Care Software Solution Prototype for Medication Prior Authorization

> **NIH NIH R41** · BREEZMED, LLC · 2020 · $301,383

## Abstract

ABSTRACT
This STTR Phase I project uses mixed-method formative evaluation strategies to develop, test, and evaluate an
alpha prototype of Breezmed, a point-of-care electronic prior authorization web-based platform. Prior
authorization burdens the current medical system, hampering a provider’s ability to efficiently prescribe
medication and in a timely fashion. This often leads to treatment non-compliance among patients and is
particularly onerous for mental illnesses, which often require rapid stabilization with prescription medication.
There is also evidence of high treatment non-compliance if medications are expensive or difficult to obtain.
Moreover, substantial empirical evidence reinforces high levels of provider burnout stemming from the tedium
required to obtain prior authorization from insurers. The lag between when the provider electronically transmits
the prescription to the pharmacy and when actual dispensing occurs burdens patients too, who routinely find out
their medication is not covered only after they have traveled to the pharmacy to obtain the medication. Recent
surveys of providers conducted by AMA and other healthcare advocacy organizations show a considerable loss
of workforce hours that could be prudently spent providing treatment, but is instead allocated to peer-to-peer
consultations or completing forms required for insurance approval. These manual processes consume precious
time and resources and detract from needed clinical practice time. Breezmed offers a software-as-a-solution
web-based platform that seamlessly and securely integrates with existing electronic health record systems. The
provider initiates Breezmed at the point-of-care drawing off diagnostic information, patient treatment history,
insurance authorization requirements and formulary rules to efficiently order medication. The platform offers
considerable economic and societal benefits and can securely piggyback to existing EHRs with minimal workflow
disruption. The proposed study involves three integrated arms including a consumer preference survey
administered to a nationally recruited panel of physicians, nurse practitioners, physician assistants, and
pharmacists. From this panel sample we further recruit focus group participants to explore in greater detail
barriers to prior authorization and probe computer-mediated solutions. We also utilize key informant interviews
with hospital administrators, healthcare technology experts in medical informatics, and insurers, and use this
detailed information to construct Breezmed’s wireframe architecture. We also conduct live usability tests with a
simulated EHR and test the Application Program Interface with the EPIC medical records system to ensure
smooth linkages in a secure HIPAA compliant environment. We have partnered with H4 technology, an Omaha-
based web application development company, and also the University of Nebraska Methodology and Evaluation
Research Core to conduct the formative evaluation component...

## Key facts

- **NIH application ID:** 10079987
- **Project number:** 1R41MH124600-01
- **Recipient organization:** BREEZMED, LLC
- **Principal Investigator:** Stephen Salzbrenner
- **Activity code:** R41 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $301,383
- **Award type:** 1
- **Project period:** 2020-08-01 → 2021-07-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10079987

## Citation

> US National Institutes of Health, RePORTER application 10079987, An Economical Point-of-Care Software Solution Prototype for Medication Prior Authorization (1R41MH124600-01). Retrieved via AI Analytics 2026-05-21 from https://api.ai-analytics.org/grant/nih/10079987. Licensed CC0.

---

*[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*
