# Core C. Biological and Molecular Analysis Core

> **NIH NIH P50** · UNIVERSITY OF CALIFORNIA AT DAVIS · 2020 · $198,278

## Abstract

PROJECT SUMMARY – BIOLOGICAL AND MOLECULAR ANALYSIS CORE
The present application seeks funding to continue the MIND Institute Intellectual and Developmental
Disabilities Research Center (IDDRC) at the University of California, Davis. The IDDRC was launched in 2013
and is the newest of the 14 IDDRCs in the network. The Biological and Molecular Analysis Core (BMAC) is
designed to facilitate studies at the cellular and molecular levels investigating the mechanisms by which genetic
and environmental risk factors interact to influence brain and immune system development and function in the
context of IDD. The BMAC will achieve this goal by addressing three specific aims. Aim 1 is to provide cutting-
edge resources and expertise for analyses in neuroimmunology, cellular and molecular imaging, and
epigenomics and genomics within the context of IDD research. This aim will be addressed through a tiered
approach to services that ranges from full-service support to training of core users to enable independent use of
core facilities and resources to access to core facilities and resources for individuals with a strong working
knowledge of the technology of interest. The Core will also provide liaison support for researchers with our
partner UC Davis cores, including the Genome Center, the Center for Molecular and Genomic Imaging (CMGI),
the Mouse Biology Program (MBP), and the Institute for Regenerative Cures (IRC) Stem Cell Core. Aim 2 is to
provide education and mentoring at all levels from student to staff to senior faculty in the methods and concepts
of immunology, cellular and molecular imaging, and genomics and epigenomics. This aim will be addressed by
working with IDDRC investigators to plan their projects and ensure they understand the potential for addressing
their aims with the full range of assays and analyses available from the Core, training IDDRC project staff and
investigators in the use of selected technologies available in the Core, and offering workshops and seminars
illustrating the findings that emerge from the services of the Core. Aim 3 is to support the MIND Institute IDDRC
cores and the broader IDDRC network. This aim will be addressed by developing procedures, protocols, and
data systems that are informed by, and inform, the other MIND Institute IDDRC cores, and by providing technical
and intellectual expertise to support and expand the numerous biological and molecular IDD research studies
within the MIND Institute IDDRC and, when appropriate, the entire IDDRC network. The constitution of the BMAC
reflects the unique expertise and interdisciplinary approaches for studying IDD at the UC Davis MIND Institute
IDDRC, including state-of-the-art methodology in immunology, cellular and molecular imaging, epigenomics, and
gene X environmental interactions. The Director of the BMAC is Judy Van de Water, PhD.

## Key facts

- **NIH application ID:** 10085151
- **Project number:** 1P50HD103526-01
- **Recipient organization:** UNIVERSITY OF CALIFORNIA AT DAVIS
- **Principal Investigator:** JUDY A. VAN DE WATER
- **Activity code:** P50 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $198,278
- **Award type:** 1
- **Project period:** — → —

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10085151

## Citation

> US National Institutes of Health, RePORTER application 10085151, Core C. Biological and Molecular Analysis Core (1P50HD103526-01). Retrieved via AI Analytics 2026-05-22 from https://api.ai-analytics.org/grant/nih/10085151. Licensed CC0.

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