# Regulatory Circuits and Virulence in Candida albicans

> **NIH NIH R01** · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · 2021 · $765,121

## Abstract

The yeast Candida albicans is a normal resident of the human digestive tract. It is also the most common
fungal pathogen of humans, causing both mucosal and systemic infections, particularly in immune
compromised patients. This proposal seeks to understand how C. albicans orchestrates its many interactions
with the host. Our strategy is to approach aspects of commensalism and pathogenicity through dissection of
the transcriptional circuitry that controls these processes. Our overarching goal is to understand how C.
albicans is specialized to thrive and cause disease in many different environments of the host.

## Key facts

- **NIH application ID:** 10086037
- **Project number:** 5R01AI049187-20
- **Recipient organization:** UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
- **Principal Investigator:** ALEXANDER D JOHNSON
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $765,121
- **Award type:** 5
- **Project period:** 2001-03-01 → 2023-01-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10086037

## Citation

> US National Institutes of Health, RePORTER application 10086037, Regulatory Circuits and Virulence in Candida albicans (5R01AI049187-20). Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/grant/nih/10086037. Licensed CC0.

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