# Training in Translational Immunology Research

> **NIH NIH T32** · COLUMBIA UNIVERSITY HEALTH SCIENCES · 2021 · $307,373

## Abstract

Project Summary
The field of immunology has exploded in the past decade, mainly as a result of technical developments enabling
the study of complex organized structures and systems. Translational immunology research is immunological
research that is oriented toward human immune diseases or therapies, ultimately aiming to convert basic
discoveries made in laboratories into improved clinical therapies. Translational immunology encompasses
molecular and animal research that addresses human diseases while emphasizing studies of the human immune
system in an iterative “bench to bedside and back” approach. Because control of immunological processes is
the goal of research in cancer, infectious disease, transplantation and autoimmunity, knowledge gained in one
area is relevant to the other areas of applied immunology, resulting in a need for “horizontal translation” between
disciplines. In order to harness the revolutionary leaps that have been made in our ability to study and control
the human immune system, multidisciplinary training is needed that integrates knowledge from multiple
disciplines at the basic and clinical levels and teaches young scientists how to use and analyze big data obtained
from high throughput platforms such as next generation sequencing, proteomics, lipidomics and metabolomics.
Analyzing these datasets increasingly demands cutting-edge bioinformatics capabilities that must be integrated
into training the next generation of translational immunologists. We are proposing an integrative training program
to meet this need by bringing together 29 established investigators at Columbia University Irving Medical Center
(CUIMC) and offering mentored research opportunities in six complementary fields of immunology: basic
immunology, developmental immunology, immunity to pathogens, tumor immunology, transplantation
 .
immunology and autoimmunity. Cutting-edge research along these themes will be supported by the outstanding
Department of Systems Biology at CUIMC. We believe this comprehensive program will expose trainees to
cutting edge translational immunology research that integrates bioinformatics analyses The ultimate goal of our
program is to provide fellows with the necessary competence to become future leaders in translational
immunology.

## Key facts

- **NIH application ID:** 10086958
- **Project number:** 5T32AI148099-02
- **Recipient organization:** COLUMBIA UNIVERSITY HEALTH SCIENCES
- **Principal Investigator:** Megan Sykes
- **Activity code:** T32 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $307,373
- **Award type:** 5
- **Project period:** 2020-02-01 → 2025-01-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10086958

## Citation

> US National Institutes of Health, RePORTER application 10086958, Training in Translational Immunology Research (5T32AI148099-02). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10086958. Licensed CC0.

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