# Assessing the commercial potential of high-density electrodes with single unit recording and stimulation capabilities.

> **NIH NIH R43** · NEURAL DYNAMICS TECHNOLOGIES INC. · 2020 · $55,000

## Abstract

SF424 – Project Summary
Understanding how the brain generates certain behaviors requires an understanding of
the function of individual neurons in dynamical neural circuits. Currently, there are few
technologies available however that allow researchers to record both the activity within a
brain region, and between brain regions in the brains of awake, behaving animals. Recent
advances in microelectrode fabrication are now enabling recordings of recording
hundreds to thousands of neurons simultaneously across brain regions that will lead to
functional analyses of dynamical neural circuits. To date however, there are no
commercially available low-cost solutions for these kinds of high-density probes. In
addition, available high-density probes do not offer customization in design and layout.
Neural Dynamics Technologies develops low-cost, highly customizable, high-density
probes for acute and chronic experiments in rodents. These probes are innovative
because they rely on a new fabrication process that allows for both customization in probe
design and low-cost fabrication. Furthermore, our probes are compatible for integration
with existing commercial amplifier systems that are standardly used for both acute and
chronic experiments in rodents. The first aim of our SBIR proposal was to streamline the
design process of high-density probes such that the fabrication process will be ready to
produce a wide variety of probe designs at low cost. The second aim involves streamlining
the production methods to enable fabrication of customizable probes with broad
compatibility with existing commercial amplifier systems.
Currently, the above-mentioned aims of our Phase I proposal are largely achieved, and
to prepare for commercialization, we would like to participate in the NIH I-Corps program
so that we can determine best product-customer fit for our technology.

## Key facts

- **NIH application ID:** 10087359
- **Project number:** 3R43MH118155-01S1
- **Recipient organization:** NEURAL DYNAMICS TECHNOLOGIES INC.
- **Principal Investigator:** Ingrid van Welie
- **Activity code:** R43 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2020
- **Award amount:** $55,000
- **Award type:** 3
- **Project period:** 2018-09-18 → 2021-09-17

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10087359

## Citation

> US National Institutes of Health, RePORTER application 10087359, Assessing the commercial potential of high-density electrodes with single unit recording and stimulation capabilities. (3R43MH118155-01S1). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10087359. Licensed CC0.

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