Structural Dynamics at LCLS

NIH RePORTER · NIH · P41 · $69,260 · view on reporter.nih.gov ↗

Abstract

ABSTRACT: ADMINISTRATION AND MANAGEMENT The proposed BTRR is a collaboration between staff of the Linac Coherent Light Source (LCLS) and the staff of the existing Structural Molecular Biology (SMB) Resource at the Stanford Synchrotron Radiation Lightsource (SSRL). The proposed BTRR will be managed as a single resource under the existing LCLS organization. It will be comprised of three TR&D projects that will be centrally driven by an evolving portfolio of Driving Biomedical Projects (DBPs). Guidance from an External Advisory Committee (EAC) as well as from a local Executive Committee will be an integral part of the strategic planning of the Resource. The proposed BTRR spans the use of two existing X-ray facilities at SLAC and beamtime award will follow established processes for each lightsource, with each having separate Proposal Review Panels comprised of external experts that make recommendations to the respective management of each lightsource. The proposed BTRR will strengthen an already strong collaborative effort between SSRL-SMB and LCLS staff. The synergies between the two SLAC lightsources have been exploited for years with collaborative developments on sample delivery systems for rapid scanning, as well as common pursuits of liquid jet delivery capabilities and operations. For the proposed BTRR, SMB staff will take leading roles in some of the TR&D efforts and be involved in all aspects of the BTRR from strategic planning to technical decisions. SMB is in itself a funded Resource. The proposed BTRR will create a separate Resource that will leverage the experience and expertise of existing and future SMB staff. SMB staff will be part of the proposed Resource in a matrixed fashion, functionally reporting to the BTRR management while administratively continuing to report to SMB. Central to the coordination of these efforts will be the direct involvement of SMB in strategic planning for the proposed BTRR. This will ensure staff working on the proposed BTRR are fully integrated within the proposed BTRR efforts. The Administration and Management component of this proposal will include the creation of an External Advisory Committee as well as a Local Executive Committee which will help provide guidance to the BTRR management team. Administrative and financial management support will be provided for the BTRR via this component.

Key facts

NIH application ID
10089008
Project number
1P41GM139687-01
Recipient
STANFORD UNIVERSITY
Principal Investigator
Sebastien Boutet
Activity code
P41
Funding institute
NIH
Fiscal year
2021
Award amount
$69,260
Award type
1
Project period
2021-04-01 → 2026-03-31