# Core C- Biostatistics and Data Analysis Core

> **NIH NIH U54** · UNIVERSITY OF PENNSYLVANIA · 2021 · $969,172

## Abstract

Core C Project Summary
Core C (Quality Control/Quality Assurance and Statistical Analysis Core) primary focuses on a)
the development, implementation, and validation of “best practices” at all steps of the GCAD
data production activities; and b) the planning and performance of association meta-analyses
combining ADSP and non-ADSP datasets. Specific Aims are: (1) Evaluate variant quality
differences between original and updated calling pipelines; (2) Develop/Extend Quality
Control/Quality Assurance (QC/QA) Pipelines; (3) Quality Assurance of ADES+ADSP
Sequencing Joint Calling and Association Analysis; (4) Quality Assurance of of TOPMed+ADSP
Sequence Joint Calling and Association Analysis; (5) Developing/Extending SV Calling best
practices for ADSP sequencing data.

## Key facts

- **NIH application ID:** 10090893
- **Project number:** 2U54AG052427-06
- **Recipient organization:** UNIVERSITY OF PENNSYLVANIA
- **Principal Investigator:** Adam Christian Naj
- **Activity code:** U54 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $969,172
- **Award type:** 2
- **Project period:** 2016-04-15 → 2026-03-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10090893

## Citation

> US National Institutes of Health, RePORTER application 10090893, Core C- Biostatistics and Data Analysis Core (2U54AG052427-06). Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/grant/nih/10090893. Licensed CC0.

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