# CORE B-Data Management, Harmonization, and Information Transfer Core > **NIH NIH U54** · UNIVERSITY OF PENNSYLVANIA · 2021 · $2,654,565 ## Abstract Core B Project Summary Core B (Data Management, Harmonization, and Information Transfer Core) is responsible for facilitating analysis of Alzheimer’s Disease Sequence Project (ADSP) data and other relevant projects by processing and harmonizing all relevant genetic and functional genomics (FG) data. Core B will manage all phenotype, genotype, annotation, and analysis results, and distribute data/files to all ADSP investigators and to NIA Genetics of Alzheimer’s Data Storage Site (NIAGADS), the NIA-designated qualified access repository for AD genetics research. Specific Aims are: (1) Receive and manage all relevant genotypic, phenotypic, and functional genomic data; (2) Calling SNVs, indels and structural variants (SVs) from sequencing data; (3) Develop a GCAD haplotype reference panel with GCAD WGS data for GWAS imputation; (4) Facilitate harmonization of FG/omics data by developing best practices for data processing and coordinate harmonization of ADSP FG Program and other relevant omics data; (5) Support GCAD information technology needs and information dissemination activities. ## Key facts - **NIH application ID:** 10090894 - **Project number:** 2U54AG052427-06 - **Recipient organization:** UNIVERSITY OF PENNSYLVANIA - **Principal Investigator:** LI-SAN WANG - **Activity code:** U54 (R01, R21, SBIR, etc.) - **Funding institute:** NIH - **Fiscal year:** 2021 - **Award amount:** $2,654,565 - **Award type:** 2 - **Project period:** 2016-04-15 → 2026-03-31 ## Primary source NIH RePORTER: https://reporter.nih.gov/project-details/10090894 ## Citation > US National Institutes of Health, RePORTER application 10090894, CORE B-Data Management, Harmonization, and Information Transfer Core (2U54AG052427-06). Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/grant/nih/10090894. Licensed CC0. --- *[NIH grants dataset](/datasets/nih-grants) · CC0 1.0*