# Nursing Home Prevention of Injury in Dementia (NH PRIDE)

> **NIH NIH R01** · HEBREW REHABILITATION CENTER FOR AGED · 2021 · $475,896

## Abstract

Abstract:
Injurious falls are common, morbid, and costly for nursing home (NH) residents, particularly those with
Alzheimer’s Disease and Related Dementias (ADRD). Our long-term goal is to reduce injurious falls in NH
residents. The current proposal will develop an Injury Liason Service (ILS) intervention designed to promote
deprescribing of psychoactive and cardiometabolic drugs AND encourage osteoporosis treatment. The
intervention will address common barriers to fall prevention encountered in NH studies including fragmented
communication. The following specific aims are proposed: 1) Develop an ILS care model designed to prevent
injurious falls in NH residents using a) an automated risk calculator to identify high risk residents, b) centralized
care coordination by an Injury Liaison Nurse, and c) videoconferencing with NH staff; 2) Test the ILS’
implementation-effectiveness in four NH facilities in residents with and without ADRD; and 3) Develop the
protocol and resources for a phase 2 efficacy trial of the ILS model in 2-3 NH chains. The central hypothesis is
that the ILS model will reduce injurious falls by changing care delivery through deprescribing and increased
osteoporosis treatment. We hypothesize that implementation barriers are greater for residents with ADRD, and
that it will require iterative intervention modifications to achieve adherence in this population. We will use
experience-based co-design principles in Aim 1 to convene key stakeholders to transform the components of
the intervention into a single, pragmatic care model that could be disseminated across NH systems. In Aim 2,
we will implement the care model in four NH facilities. This will require programming the prediction model
within the EMRs to identify high risk residents. A centralized ILS nurse will enact deprescribing
recommendations and osteoporosis treatment among high risk residents (n~80) from a remote location.
Videoconferencing will be used to facilitate education and communication. We will measure implementation
success using post intervention measures of acceptability, demand, fidelity, and practicality. Effectiveness will
be measured using process measures (e.g., medication dose reduction) using a pre-post design, and safety
will be assessed using both pre-post measures from the Minimum Data Set (MDS) and chart review, stratified
by ADRD status. In addition, we will validate the planned primary outcome for a future pragmatic trial, injurious
falls ascertained from the MDS, with chart review. In Aim 3, we will develop the protocol and all materials
needed for conducting an embedded pragmatic clinical trial of the ILS within 2-3 NH chains. The research team
has considerable experience with NH research, including implementation science. At the completion of this
study, we will have developed a robust care model that can be readily deployed by NH systems and evaluated
for its impact on injurious falls in ADRD residents. We will be ideally positioned to conduct a ...

## Key facts

- **NIH application ID:** 10092886
- **Project number:** 5R01AG062492-03
- **Recipient organization:** HEBREW REHABILITATION CENTER FOR AGED
- **Principal Investigator:** Sarah Dyer Berry
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $475,896
- **Award type:** 5
- **Project period:** 2019-05-01 → 2024-01-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10092886

## Citation

> US National Institutes of Health, RePORTER application 10092886, Nursing Home Prevention of Injury in Dementia (NH PRIDE) (5R01AG062492-03). Retrieved via AI Analytics 2026-05-27 from https://api.ai-analytics.org/grant/nih/10092886. Licensed CC0.

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