# Tumor Tissue and Pathology Shared Resource

> **NIH NIH P30** · WAKE FOREST UNIVERSITY HEALTH SCIENCES · 2021 · $99,457

## Abstract

TUMOR TISSUE AND PATHOLOGY SHARED RESOURCE 
Project Summary 
The Tumor Tissue and Pathology Shared Resource (TTPSR) consists of three well-integrated laboratories, the 
Tumor Tissue Lab, the Human Pathology Lab, and the Comparative Pathology Lab, with one reception point 
for seamless operations. The Co-Directors of the Shared Resource are Edward Levine, M.D., and Barry 
DeYoung, M.D. The Managers of the three laboratories are Greg Kucera, Ph.D., (Tumor Tissue Lab), Shadi 
Qasem, M.D., (Human Pathology Lab), and David Caudell, D.V.M., Ph.D. (Comparative Pathology Lab). There 
are 6 technical staff members supporting the Shared Resource for a combined 4.16 FTE. The mission of the 
TTPSR is to facilitate translational cancer research by collecting and supplying high-quality, well-characterized 
human and animal tissues (neoplastic and normal); and providing pathology services to Wake Forest Baptist 
Comprehensive Cancer Center (WFBCCC) members. The Specific Aims of the TTPSR are to: 1) Collect and 
supply high-quality, well-characterized human and animal tissues (neoplastic and normal); 2) Provide scientific 
and pathological expertise related to tissue collection, processing, histological and immunological staining, and 
evaluation to support the development of clinical protocols, grant applications, and manuscripts; and 3) Provide 
pathology services for human and animal tissues for cancer investigations. Since the last competing renewal, 
the TTPSR has been enhanced by the addition of the Human and Comparative Pathology Laboratories, which 
provide much-needed resources to WFBCCC investigators. The Human Pathology Lab works closely with the 
Tumor Tissue Lab for quality control of samples and provides clinical pathology expertise to investigators. The 
Comparative Pathology Lab provides unique samples and pathology expertise for a variety of experimental 
animals ranging from rodents to non-human primates. These labs are equipped with state-of-the-art 
instrumentation that are overseen by certified pathologists and trained staff. The TTPSR maintains a web- 
based database for interaction of investigators with Shared Resource personnel and provides access to 
banked tissue inventories. At present, TTPSR has available over 44,180 tissue samples and collects tissues 
from approximately 1,100 patients per year. The Shared Resource provided services to 13 members during the 
most recent funding period: all of its users were WFBCCC members; 69% of whom have peer-reviewed 
funding. In the previous funding period (2006-2011), 261 samples were distributed, compared with 1001 
samples for the current funding period (2011-2015), representing a 3.8-fold increase.

## Key facts

- **NIH application ID:** 10092995
- **Project number:** 5P30CA012197-46
- **Recipient organization:** WAKE FOREST UNIVERSITY HEALTH SCIENCES
- **Principal Investigator:** EDWARD A LEVINE
- **Activity code:** P30 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $99,457
- **Award type:** 5
- **Project period:** 1997-02-01 → 2022-01-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10092995

## Citation

> US National Institutes of Health, RePORTER application 10092995, Tumor Tissue and Pathology Shared Resource (5P30CA012197-46). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10092995. Licensed CC0.

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