# Steroselectivity of Synthetically Valuable Enzyme Catalysts

> **NIH NIH R01** · UNIVERSITY OF CALIFORNIA LOS ANGELES · 2021 · $292,995

## Abstract

Project Abstract
This research program develops and applies state-of-the-art computational methods to
understand stereoselectivities of enzyme catalysts for reactions of high synthetic value.
The control of stereoselectivity is an essential feature of efficient synthesis, and this
program provides explanations of the origins of these selectivities and builds on these to
predict new enzyme catalysts for stereoselective reactions. Collaborators test these
predictions. These are critical elements in the synthesis of effective pharmaceutical
agents.

## Key facts

- **NIH application ID:** 10104515
- **Project number:** 5R01GM124480-04
- **Recipient organization:** UNIVERSITY OF CALIFORNIA LOS ANGELES
- **Principal Investigator:** KENDALL N HOUK
- **Activity code:** R01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $292,995
- **Award type:** 5
- **Project period:** 2018-04-01 → 2022-02-28

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10104515

## Citation

> US National Institutes of Health, RePORTER application 10104515, Steroselectivity of Synthetically Valuable Enzyme Catalysts (5R01GM124480-04). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10104515. Licensed CC0.

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