# Supporting Patients and Family Care Partners to Manage Chronic Kidney Disease Together

> **NIH NIH K01** · DUKE UNIVERSITY · 2021 · $120,220

## Abstract

PROJECT SUMMARY
Candidate: Nicole DePasquale, PhD, MSPH, is an Assistant Professor at the Duke University School of
Medicine and is fully committed to becoming an independently-funded investigator at the intersection of
family science and disease management. Her long-term career goal is to develop family-centered interventions
that optimize individual and dyadic health and well-being among older patients with chronic disease and their
family care partners. Dr. DePasquale’s multidisciplinary background makes her an ideal candidate to merge
these two largely separate areas of inquiry. Her academic, research, and training experiences to date span the
fields of communication, psychology, sociology, public health, and human development and family studies, and
her research experiences have been both quantitative and qualitative in nature.
Career development and training plan: Dr. DePasquale’s career development and training plan feature a
multidisciplinary mentoring team comprising a general internist/clinical epidemiologist, geriatrician, health
services researcher, biostatistician, social/health psychologist, and board-certified nephrologist. This team will
support her pursuit of activities that address gaps and strengthen under-developed areas in her experience
through a training plan focused on: 1) geriatric nephrology, 2) dyadic disease management, 3) advanced
quantitative and qualitative research methodology, 4) intervention science, and 5) professional and scholarly
development (best research practices, research collaborations, leadership, and grant writing). Additional
resources to foster her career development and facilitate achievement of her training goals include Duke’s
Claude D. Pepper Center; Edward R. Roybal Center; Offices for Faculty Development, Scientific Integrity, and
Research Mentoring; Social Science Research Institute; and Clinical Research Training Program.
Research plan: The proposed research will use different methodological to address the overarching objective of
understanding the ways in which older patients and their family care partners manage the full course of
chronic kidney disease (CKD) together, and how dyadic management affects individual and dyadic health and
well-being: 1) quantify associations between care partner help with CKD self-management and patient self-
management, depressive symptoms, and health-related quality of life over time (secondary data analysis); 2)
investigate the interrelations of dyadic disease appraisal, disease management, and health along the continuum
of CKD progression (primary data collection through interviews); and 3) adapt and test the feasibility of
SHARE for CKD, a care planning intervention to help patient-care partner dyads work together to manage
CKD. The goal of this work is to initiate a shift in focus from individual experiences and outcomes related to
CKD self-management to those of both members of the care dyad, which can then be used to assist research,
clinical care, and ...

## Key facts

- **NIH application ID:** 10104708
- **Project number:** 1K01AG070284-01
- **Recipient organization:** DUKE UNIVERSITY
- **Principal Investigator:** Nicole DePasquale
- **Activity code:** K01 (R01, R21, SBIR, etc.)
- **Funding institute:** NIH
- **Fiscal year:** 2021
- **Award amount:** $120,220
- **Award type:** 1
- **Project period:** 2021-04-01 → 2026-01-31

## Primary source

NIH RePORTER: https://reporter.nih.gov/project-details/10104708

## Citation

> US National Institutes of Health, RePORTER application 10104708, Supporting Patients and Family Care Partners to Manage Chronic Kidney Disease Together (1K01AG070284-01). Retrieved via AI Analytics 2026-05-23 from https://api.ai-analytics.org/grant/nih/10104708. Licensed CC0.

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